(2S)-Methyl 2-N-benzoylamino-5-methylhex-4-enoate | 1236113-73-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2S)-Methyl 2-N-benzoylamino-5-methylhex-4-enoate
• 英文别名: Methyl 2-benzamido-5-methylhex-4-enoate
• CAS: 1236113-73-7
• 化学式: C₁₅H₁₉NO₃
• 分子量: 261.321
• InChiKey: HHOGIMANRZMGBY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  55.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Methods for the Synthesis of Dicarba Bridges in Organic Compounds
  申请人：Robinson Andrea Jane

  公开号：US20100036089A1

  公开（公告）日：2010-02-11

  The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.

  本发明涉及有机化合物中形成二碳桥的方法。这涉及在有机化合物上使用一对互补的可交换基团，并在微波辐射条件下使化合物经历交叉重合反应。或者，化合物在一对交叉重合基团之间含有一个转向诱导基团，以促进交叉重合反应。
• METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN ORGANIC COMPOUNDS
  申请人：Robinson Andrea Jane

  公开号：US20130023645A1

  公开（公告）日：2013-01-24

  The present invention related to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds containing a turn-induced group between the pair of cross metathesisable groups to facilitate the cross-metathesis.

  本发明涉及有机化合物中形成双碳桥的方法。这涉及使用有机化合物中一对互补的可交换基团，并在微波辐射条件下将化合物置于交叉交换反应中。另一种选择是，在一对交叉交换基团之间含有一个转向诱导基团的化合物，以促进交叉交换反应。
• Conotoxin analogues, and methods for synthesis of intramolecular dicarba bridge containing peptides
  申请人：Syngene Limited

  公开号：EP1984384B1

  公开（公告）日：2015-10-21
• Methods for the synthesis of two or more dicarba bridges in organic compounds
  申请人：Syngene Limited

  公开号：EP1984386B1

  公开（公告）日：2013-10-09
• US9102708B2
  申请人：——

  公开号：US9102708B2

  公开（公告）日：2015-08-11