| 1338371-49-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1338371-49-5
• 化学式: C₁₅H₁₈N₄OS
• 分子量: 302.4
• InChiKey: UUIHAGLYGJRZGO-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  、 2'-溴-4-氯苯乙酮 在 potassium carbonate 作用下， 以 乙醇 为溶剂， 生成 [3-amino-4-(4-methoxyphenylazo)-5-piperidinothiophen-2-yl](4-chlorophenyl)methanone
  参考文献：
  名称：

  荧光介离子 1-(2-aryl-4H-thieno[3,4-d][1,2,3]triazol-2-ium-4-ylidene)ethan-1-olates：一锅合成、光物理学和生物学行为

  摘要：

  本文报道了一种稀有类型的介离子化合物的一锅法合成，这些化合物是缩合介离子。采用改进的合成方法合成了一系列新型双环芳基噻吩并三唑鎓盐。这种方法具有广泛的起始材料，用于获得具有出色光物理特性的多种结构。装饰介离子环的取代基模式是决定合成化合物电子分布的重要因素。拉-拉 (А-π-A)、推-推 (D-π-D)、拉-推 (A-π-D) 和推-拉 (D-π-A) 系统被设计、合成和研究了它们的吸收、发射、稳定性和生物学行为。进行了量子化学计算，以加深对这些系统吸收和发射特性的了解，并解释它们不寻常的几何形状和电子结构。共聚焦显微镜实验表明，噻吩并三唑鎓酸盐很容易渗透到活细胞中，并选择性地聚集在细胞膜、高尔基体和内质网附近。

  DOI：

  10.1016/j.dyepig.2021.109777

文献信息

• 1,3-Dipolar cycloaddition of 3-alkylsulfanyl-2-arylazo-3-(tert-cycloalkylamino)acrylonitriles with N-methyl- and N-phenylmaleimides
  作者：Nataliya P. Belskaya、Svetlana G. Lesogorova、Julia O. Subbotina、Aleksandr V. Koksharov、Pavel A. Slepukhin、Wim Dehaen、Vasiliy A. Bakulev

  DOI：10.1016/j.tet.2014.12.087

  日期：2015.3

  A series of 1,2-diaza-1,3-butadienes with terminal S,N-acetal function were obtained and reacted with N-methyl- and N-phenylmaleimides. As a result of the 1,3-dipolar cycloaddition, a range of new functionalized nonaromatic heterocyclic compounds including: octahydro-1H-pyrrolo[3,4-a]indolizine, octahydropyrrolo[3',4':3,4]pyrrolo[1,2-a]azepine, hexahydropyrrolo[3',41:3,4]pyrrolo[2,1-c][1,4]oxazine and -thiazine, were obtained with good yields in mild conditions. Experimental and theoretic results allowed establishment of a relationship between the structures of the tert-cycloallcylamine group and the activity of the azomethine ylides generated. (C) 2014 Elsevier Ltd. All rights reserved.
• Synthesis and oxidative cyclization of 3-amino-2-arylazo-5-tert-cycloalkylaminothiophenes
  作者：N. P. Belskaya、A. V. Koksharov、A. I. Eliseeva、Z. Fan、V. A. Bakulev

  DOI：10.1007/s10593-011-0799-8

  日期：2011.8

  A series of 3-amino-4-arylazo-4,5-dihydrothiophenes has been synthesized by the reaction of aryl-hydrazonocyanothioacetamides (containing a tert-cycloalkylamino group) with alpha-halo ketones, 2-chloroacetonitrile, or 4-nitrobenzyl bromide. Their oxidation in the presence of metal acetates was investigated. It was shown that heating in pyridine with Cu(OAc)(2) leads to the formation of thieno[3,4-d]-1,2,3-triazoliumolates.