N-tert-butyl-1,1-bis(4-chlorophenyl)methanimine | 27126-15-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-tert-butyl-1,1-bis(4-chlorophenyl)methanimine
• 英文别名: 4,4'-Dichlor-N-t-butylbenzophenonimin
• CAS: 27126-15-4
• 化学式: C₁₇H₁₇Cl₂N
• 分子量: 306.235
• InChiKey: UDQIUZQUQCJMGM-UHFFFAOYSA-N

物化性质

• 沸点：
  369.9±42.0 °C(Predicted)
• 密度：
  1.11±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.63
• 重原子数：
  20.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  12.36
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  异氰酸叔丁酯 、 tetrakis(4-chlorophenyl)plumbane 在 palladium diacetate 作用下， 以 甲苯 为溶剂， 反应 2.0h， 以50%的产率得到N-tert-butyl-1,1-bis(4-chlorophenyl)methanimine
  参考文献：
  名称：

  Palladium-Catalyzed Diarylation of Isocyanides with Tetraarylleads for the Selective Synthesis of Imines and α-Diimines

  摘要：

  Using tetraaryllead compounds (PbAr4) as arylating reagents, isocyanides undergo selective diarylation in the presence of palladium catalysts such as Pd(OAc)(2) or Pd(PPh3)(4) to afford imines and/or alpha-diimines based on the isocyanide employed. With aliphatic isocyanides, imines are obtained preferentially, whereas alpha-diimines are formed in the case of electron-rich aromatic isocyanides. The differences in imine/alpha-diimine selectivity can be attributed to the stability of imidoylpalladium intermediates formed in this catalytic reaction. Compared with other arylating reagents, tetraaryllead compounds are excellent candidates for use in the selective transformations to imines and/or alpha-diimines, especially in terms of inhibiting the oligomerization of isocyanides, which results in a lower product selectivity in many transition-metal-catalyzed reactions of isocyanides.

  DOI：

  10.1021/acs.joc.9b01639

文献信息

• A Convenient Method for the Preparation of N-Alkyl Benzophenone Imines
  作者：I. MORETTI、G. TORRE

  DOI：10.1055/s-1970-21584

  日期：——
• OXIME ETHER COMPOUND AND APPLICATION THEREOF
  申请人：SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD.

  公开号：US20220400678A1

  公开（公告）日：2022-12-22

  The present invention discloses an oxime ether compound with novel structure. The structure is shown in general formula I. The definition of each substituent in the formula is provided in the description. The compound of general formula I has excellent microbicidal 1 activity, and has good control effects on plant bacterial diseases and fungal diseases. The present invention comprises an application of the compound of the general formula I as a microbicide in agriculture and other fields.