(N,N'-bis(salicylidene)-2,3-diiminopyridineato)copper(II) | 190595-61-0

• 分子结构分类: 有机化合物 - 苯类化合物
• 英文名称: (N,N'-bis(salicylidene)-2,3-diiminopyridineato)copper(II)
• 英文别名: [Cu(DAPY-(Sal)2)]；[Cu(2,3-Salpyr)]
• CAS: 190595-61-0
• 化学式: C₁₉H₁₃CuN₃O₂
• 分子量: 378.877
• InChiKey: FIDXDWIVVXFKTK-GEIVNNGUSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  copper diacetate 、 N,N′-bis(salicyliden)-2,3-diaminopyridine 以 乙醇 为溶剂， 以39%的产率得到(N,N'-bis(salicylidene)-2,3-diiminopyridineato)copper(II)
  参考文献：
  名称：

  Synthesis and Anti-Bacterial/Catalytic Properties of Schiff Bases and Schiff Base Metal Complexes Derived from 2,3-Diaminopyridine

  摘要：

  DOI：

  10.1080/00945710009351817

文献信息

• Synthesis, characterization and thermodynamics of complex formation of some new Schiff base ligands with some transition metal ions and the adduct formation of zinc Schiff base complexes with some organotin chlorides
  作者：Mozaffar Asadi、Zahra Asadi、Susan Torabi、Najmeh Lotfi

  DOI：10.1016/j.saa.2012.03.061

  日期：2012.8

  spectrophotometric study of the adduct formation of the zinc(II) complexes, [Zn(2,3-Salpyr)] and [Zn(3,4-Salpyr)], as donor with R2SnCl2 (R = methyl, phenyl, n-butyl), PhSnCl3 and Bu3SnCl as acceptors has been investigated in methanol, as solvent. The formation constants and the thermodynamic free energies were measured using UV–vis spectrophotometry. Titration of the organotin chlorides with Zn(II) complexes

  合成了四个新的配合物[M（Salpyr）]，其中Salpyr = N，N'-双（水杨基）-2,3-和3,4-二亚氨基吡啶，M = Co，Cu，Mn，Ni和Zn 1 H NMR，IR光谱，元素分析和紫外可见分光光度法。紫外可见分光光度法研究作为供体与R 2 SnCl 2（R =甲基）形成的锌（II）配合物[Zn（2,3-Salpyr）]和[Zn（3,4-Salpyr）]加合物的形成，苯基，正丁基），PhSnCl 3和Bu 3 SnCl作为受体已在甲醇（作为溶剂）中进行了研究。使用紫外可见分光光度法测量形成常数和热力学自由能。在不同温度下用Zn（II）络合物滴定有机锡氯化物（T = 283–313 K）导致形成1：1加合物。结果表明，随着温度的升高，形成常数减小。R n SnCl 4- n作为受体对给定的锌络合物的反应趋势如下：PhSnCl 3  > Me 2 SnCl 2  > Ph 2 SnCl
• Experimental and theoretical studies on Cu(II) complex of N,N′-disalicylidene-2,3-diaminopyridine ligand reveal indirect evidence for DNA intercalation
  作者：Abdulkadir Kocak、Hakan Yilmaz、Ozlem Faiz、Omer Andac

  DOI：10.1016/j.poly.2015.11.037

  日期：2016.1

  A potential DNA intercalating Cu(II) complex ([CuL]) of the N,N'-disalicylidene-2,3-diaminopyridine ligand (H2L; dianion =L2- has been synthesized and characterized. The photophysical and the DNA binding behaviors of the neutral [CuL] have been investigated both experimentally and theoretically. Experimental studies reveal that the [CuL] has a quite strong interaction with the Calf Thymus DNA (ctDNA) with K-b = (1.53 +/- 0.48) x 10(6). Experimental bathochromism of 4 nm and hypochromism of similar to 50% on the absorption band of the [CuL] at 408 nm by intercalation were reproduced by calculations. The competitive displacement experiments were carried out using Methylene Blue (MB) and Ethidium Bromide (EB). Viscosity measurements totally supported the intercalative interaction. Quantum mechanical calculations using time dependent density functional theory (TDDFT) coupled with polarizable continuum model were carried out in the proposed dimer of deoxyguanosine-monophosphate-deoxycytidine, d(GpC)2, intercalation pocket. The calculations qualitatively confirmed the intercalative binding. In addition, vertical excitation calculations showed that electronic excitations of H2L are affected by the environment and Cu2+ ion. The electronic transitions of the [CuL] are involved in mostly pi-pi* transitions but includes significant contribution from the charge transfer. According to the calculations, the electronic spectrum of the [CuL] is sensitive to the DNA intercalation because of the pi-pi stacking interaction between the DNA base pairs and aromatic rings of the [CuL]. (C) 2015 Elsevier Ltd. All rights reserved.