1-(Henicosafluorodecyl)undecane | 125635-86-1

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1-(Henicosafluorodecyl)undecane
• 英文别名: 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-henicosafluorohenicosane
• CAS: 125635-86-1
• 化学式: C₂₁H₂₃F₂₁
• 分子量: 674.4
• InChiKey: YKNQZBAXZDMIMH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13
• 重原子数：
  42
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  21

文献信息

• [EN] METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS<br/>[FR] PROCÉDÉS ET COMPOSÉS POUR L'IDENTIFICATION D'INHIBITEURS DE GLYCOSYLTRANSFÉRASE
  申请人：HARVARD COLLEGE

  公开号：WO2013151697A1

  公开（公告）日：2013-10-10

  The present invention provides moenomycin-based probe compounds of Formula (I) for use in screening inhibitors of bacterial glycosyltransferases. The present invention also provides bacterial glycosyltransferase screening assays using compounds of Formula (I).

  本发明提供了用于筛选细菌糖基转移酶抑制剂的以莫诺霉素为基础的探针化合物的公式(I)。本发明还提供了使用公式(I)化合物进行细菌糖基转移酶筛选的检测方法。
• [EN] CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS<br/>[FR] PROCÉDÉS CHIMIO-ENZYMATIQUES POUR SYNTHÉTISER DES ANALOGUES DE LA MOÉNOMYCINE
  申请人：HARVARD COLLEGE

  公开号：WO2013152279A1

  公开（公告）日：2013-10-10

  The present invention provides methods of synthesizing moenomycin analogs of Formula (I). The present invention also provides compositions comprising a compound of Formula (I) and kits for synthesizing compounds of Formula (I).

  本发明提供了合成式(I)的莫诺霉素类似物的方法。本发明还提供了包含式(I)化合物的组合物和用于合成式(I)化合物的试剂盒。
• METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS
  申请人：President and Fellows of Harvard College

  公开号：US20150079618A1

  公开（公告）日：2015-03-19

  The present invention provides moenomycin-based probe compounds of Formula (I) for use in screening inhibitors of bacterial glycosyltransferases. The present invention also provides bacterial glycosyltransferase screening assays using compounds of Formula (I).
• CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS
  申请人：President and Fellows of Harvard College

  公开号：US20150119561A1

  公开（公告）日：2015-04-30

  The present invention provides methods of synthesizing moenomycin analogs of Formula (I). The present invention also provides compositions comprising a compound of Formula (I) and kits for synthesizing compounds of Formula (I).
• MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF
  申请人：President and Fellows of Harvard College

  公开号：US20150119354A1

  公开（公告）日：2015-04-30

  The present invention provides compounds of Formula (I); or a pharmaceutically acceptable form thereof; wherein R 1, R 2 ,R 3 ,R 6 ,R 7 ,R 12 ,R a , and R b are as defined herein, and G is a group of Formula (a), (b), or (c): Formula (II), wherein X 1 ; X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , Y, R C , R d , R z , a, d, e, x, n, and m are as defined herein. The present invention further provides pharmaceutical compositions comprising a compound of Formula (I), kits comprising such compositions, methods of use and treatment, and preparative methods.