2-oxoacetyl-benzoic acid | 103029-88-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-oxoacetyl-benzoic acid
• 英文别名: 2-Glyoxyloyl-benzoesaeure；Phenylglyoxal-o-carbonsaeure；o-Carboxyphenyl glyoxal；2-oxaldehydoylbenzoic acid
• CAS: 103029-88-5
• 化学式: C₉H₆O₄
• 分子量: 178.144
• InChiKey: BVNXSQRWQGKXQJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  71.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-oxoacetyl-benzoic acid 、 邻苯二胺 在 盐酸 作用下， 生成 2-quinoxalin-2-yl-benzoic acid
  参考文献：
  名称：

  LORENTZ SPACES OF VECTOR-VALUED MEASURES

  摘要：

  Given a non-atomic, finite and complete measure space (Omega, Sigma, mu) and a Banach space X, the modulus of continuity for a vector measure F is defined as the function omega(F)(t) = sup(mu(E)less than or equal tot) \F\(E) and the space V-p,V-q(X) of vector measures such that t(-1/p)'omega(F)(t) is an element of L-q((0,mu(Omega)],dt/t) is introduced. It is shown that V-p,V-q(X) contains isometrically L-q,L-p(X) and that L-p,L-q(X) = V-p,V-q(X) if and only if X has the Radon-Nikodym property. It is also proved that Vp,q (X) coincides with the space of cone absolutely summing operators from L-p',L-q' into X and the duality V-p,V-q(X*) = (L-p',L-q'(X))* where 1/p + 1/p' = 1/q + 1/q' = 1. Finally, V-p,V-q(X) is identified with the interpolation space obtained by the real method (V-1(X), V-infinity(X))(1/p)',(q). Spaces where the variation of F is replaced by the semivariation are also considered.

  DOI：

  10.1112/s0024610703004198
• 作为产物：
  描述：

  1,4-萘醌 生成 2-oxoacetyl-benzoic acid
  参考文献：
  名称：

  LORENTZ SPACES OF VECTOR-VALUED MEASURES

  摘要：

  Given a non-atomic, finite and complete measure space (Omega, Sigma, mu) and a Banach space X, the modulus of continuity for a vector measure F is defined as the function omega(F)(t) = sup(mu(E)less than or equal tot) \F\(E) and the space V-p,V-q(X) of vector measures such that t(-1/p)'omega(F)(t) is an element of L-q((0,mu(Omega)],dt/t) is introduced. It is shown that V-p,V-q(X) contains isometrically L-q,L-p(X) and that L-p,L-q(X) = V-p,V-q(X) if and only if X has the Radon-Nikodym property. It is also proved that Vp,q (X) coincides with the space of cone absolutely summing operators from L-p',L-q' into X and the duality V-p,V-q(X*) = (L-p',L-q'(X))* where 1/p + 1/p' = 1/q + 1/q' = 1. Finally, V-p,V-q(X) is identified with the interpolation space obtained by the real method (V-1(X), V-infinity(X))(1/p)',(q). Spaces where the variation of F is replaced by the semivariation are also considered.

  DOI：

  10.1112/s0024610703004198

文献信息

• MODIFIED LYSINE OR ARGININE CONTAINING PROTEINS AND PEPTIDES
  申请人：THE NEW YORK BLOOD CENTER

  公开号：EP0820295A1

  公开（公告）日：1998-01-28
• EP0820295A4
  申请人：——

  公开号：EP0820295A4

  公开（公告）日：1998-06-10
• [EN] MODIFIED LYSINE OR ARGININE CONTAINING PROTEINS AND PEPTIDES<br/>[FR] PROTEINES ET PEPTIDES RENFERMANT DE LA LYSINE OU DE L'ARGININE MODIFIEE
  申请人：NEW YORK BLOOD CENTER

  公开号：WO1996032124A1

  公开（公告）日：1996-10-17

  (EN) A composition is provided which comprises a protein or peptide containing lysines, wherein at least one of the lysines and/or the N-terminal amino group of the protein or peptide, such as casein, $g(b)-lactoglobulin, powdered milk or whey, is modified by contact with an aromatic acid anhydride compound, such as trimellitic anhydride, trimellitic anhydride chloride or 3-hydroxyphthalic anhydride. Additionally a composition is provided wherein a protein or peptide containing arginines is modified by an arginine modifying agent containing at least one carboxyl group, such as p-carboxyphenylglyoxal. The compositions are capable of binding to CD4 cell receptors, such as HIV-1 or HIV-2 binding site on CD4 cell receptors. The compositions are thus useful for the prevention of HIV-1 or HIV-2 infection, especially by local administration.(FR) Composition comprenant une protéine ou un peptide renfermant des lysines, dans des conditions telles que les lysines et/ou le groupe amino à terminaison N de la protéine ou du peptide, comme la caséine, la $g(b)-lactoglobuline, le lait en poudre ou le petit lait, soient modifiés par le contact d'un composé d'anhydride d'acide aromatique, comme l'anhydride trimellitique, le chlorure d'anhydride trimellitique ou l'anhydride 3-hydroxyphtalique. L'invention porte également sur une composition dans laquelle une protéine ou un peptide renfermant des arginines modifiées par un agent modificateur de l'arginine renfermant au moins un groupe carboxyl, comme le p-carboxyphénylglyoxal. Ces compositions peuvent se lier aux récepteurs cellulaires CD4, comme le site de liaison du VIH-1 ou du VIH-2 sur les récepteurs cellulaires CD4. Ces compositions se révèlent ainsi utiles pour la prévention des infections par VIH-1 ou VIH-2, surtout par administration locale.
• [EN] METHODS OF TREATING HERPES OR CHLAMYDIA<br/>[FR] METHODES DE TRAITEMENT DE L'HERPES ET DES INFECTIONS A CHLAMYDIA
  申请人：NEW YORK BLOOD CENTER

  公开号：WO1997034619A1

  公开（公告）日：1997-09-25

  (EN) A method of preventing the transmission of or treating herpesvirus, such as herpes simplex virus infection, or preventing the transmission of or treating $i(Chlamydia trachomatis), comprising administering to a patient a composition which comprises: (i) a protein or peptide containing lysines and an N-terminal amino group, wherein at least one of the lysines or the N-terminal amino group of the protein or peptide, such as casein, $g(b)-lactoglobulin, powdered milk or whey, is modified by contact with an aromatic acid anhydride compound, such as trimellitic anhydride, trimellitic anhydride chloride or 3-hydroxyphthalic anhydride and/or (ii) a protein or peptide containing arginines, which is modified by an arginine modifying agent containing at least one carboxyl group, such as p-carboxyphenylglyoxal.(FR) Méthode permettant de prévenir la transmission du virus de l'herpès ou de traiter des infections par ledit virus, telles qu'une infection par virus de l'herpès simplex, ou de prévenir la transmission de $i(Chlamydia trachomatis) ou de traiter des infections par ladite $i(Chlamydia), qui consiste en l'administration à un patient d'une composition comprenant: (i) une protéine ou un peptide contenant des lysines et un groupe amino N-terminal, où au moins les lysines ou un groupe amino N-terminal de la protéine ou du peptide, caséine, $g(b)-lactoglobuline, lait ou petit lait en poudre par exemple, est modifié par contact avec un composé anhydride acide aromatique, tel que l'anhydride trimellitique, le chlorure anhydre trimellitique ou l'anhydride 3-hydroxyphtalique par exemple; et/ou (ii) une protéine ou un peptide contenant des arginines, qui est modifié par un agent modifiant l'arginine contenant au moins un groupe carboxyle, le p-carboxyphénylglyoxal par exemple.
• LORENTZ SPACES OF VECTOR-VALUED MEASURES
  作者：OSCAR BLASCO、PABLO GREGORI

  DOI：10.1112/s0024610703004198

  日期：2003.6

  Given a non-atomic, finite and complete measure space (Omega, Sigma, mu) and a Banach space X, the modulus of continuity for a vector measure F is defined as the function omega(F)(t) = sup(mu(E)less than or equal tot) \F\(E) and the space V-p,V-q(X) of vector measures such that t(-1/p)'omega(F)(t) is an element of L-q((0,mu(Omega)],dt/t) is introduced. It is shown that V-p,V-q(X) contains isometrically L-q,L-p(X) and that L-p,L-q(X) = V-p,V-q(X) if and only if X has the Radon-Nikodym property. It is also proved that Vp,q (X) coincides with the space of cone absolutely summing operators from L-p',L-q' into X and the duality V-p,V-q(X*) = (L-p',L-q'(X))* where 1/p + 1/p' = 1/q + 1/q' = 1. Finally, V-p,V-q(X) is identified with the interpolation space obtained by the real method (V-1(X), V-infinity(X))(1/p)',(q). Spaces where the variation of F is replaced by the semivariation are also considered.