N-(3,5-dimethoxyphenyl)-4-(2-oxo-3-propylimidazolidin-1-yl)benzenesulfonamide | 1328952-95-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: N-(3,5-dimethoxyphenyl)-4-(2-oxo-3-propylimidazolidin-1-yl)benzenesulfonamide
• CAS: 1328952-95-9
• 化学式: C₂₀H₂₅N₃O₅S
• 分子量: 419.502
• InChiKey: BQJSOQVOAYOGKQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  29
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  96.6
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] SUBSTITUTED 2-IMIDAZOLIDINONES AND 2-IMIDAZOLONES AND THEIR USE IN THE TREATMENT OF CANCER<br/>[FR] 2-IMIDAZOLIDINONES ET 2-IMIDAZOLONES SUBSTITUÉES ET LEUR UTILISATION DANS LE TRAITEMENT DU CANCER
  申请人：UNIV LAVAL

  公开号：WO2013023274A1

  公开（公告）日：2013-02-21

  Compounds of formula (I) wherein R1, R4, R8, X and Y as defined herein are provided as useful for the inhibition of certain types of cancer cells, amongst others, breast cancer cells, or for the manufacture of anti-cancer agents.

  式(I)中的化合物，其中R1、R4、R8、X和Y如本文所定义的那样，被提供为抑制某些类型的癌细胞（包括乳腺癌细胞等）或用于制造抗癌药物。
• SUBSTITUTED 2-IMIDAZOLIDINONES AND 2-IMIDAZOLONES AND THEIR USE IN THE TREATMENT OF CANCER
  申请人：Université Laval

  公开号：EP2744786A1

  公开（公告）日：2014-06-25
• SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS
  申请人：Gaudreault René C.

  公开号：US20120309777A1

  公开（公告）日：2012-12-06

  Compounds of formula (I): wherein R 1 , R 2 , R 3 , R 4 , R 7 , R 6 , R 7 , R 8 , R 9 , A, X and Y as defined herein are provided as useful for the treatment of cancer or for the manufacture of anti-cancer agents.
• Substituted 2-Imidazolidinones and 2-Imidazolones and Their Use in the Treatment of Cancer
  申请人：C.-Gaudreault Rene

  公开号：US20140315968A1

  公开（公告）日：2014-10-23

  Compounds of formula (I) wherein R 1 , R 4 , R 8 , X and Y as defined herein are provided as useful for the inhibition of certain types of cancer cells, amongst others, breast cancer cells, or for the manufacture of anti-cancer agents.
• US9034888B2
  申请人：——

  公开号：US9034888B2

  公开（公告）日：2015-05-19