(2-Bromo-5-hydroxy-phenyl)methyl acetate | 2251695-12-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2-Bromo-5-hydroxy-phenyl)methyl acetate
• 英文别名: (2-bromo-5-hydroxyphenyl)methyl acetate
• CAS: 2251695-12-0
• 化学式: C₉H₉BrO₃
• 分子量: 245.07
• InChiKey: NGYNDZJBYHSCCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF<br/>[FR] PROCÉDÉ DE PRÉPARATION DE 5-(4-CYANOPHÉNOXY)-1,3-DIHYDRO-1-HYDROXY- [2,1]-BENZOXABOROLE ET SES POLYMORPHES
  申请人：MSN LABORATORIES PRIVATE LTD R&D CENTER

  公开号：WO2018216032A1

  公开（公告）日：2018-11-29

  The present invention relates to process for the preparation of 5-(4-cyano phenoxy)-1,3-dihydro-1-hydroxy-[2, 1]-benzoxaborole represented by the following structural formula- 1 and polymorphs thereof. The present invention also relates to salts of 5-(4-cyano phenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and process for their preparation and their use in the preparation of pure compound of the formula- 1.

  本发明涉及一种制备5-(4-氰基苯氧基)-1,3-二氢-1-羟基-[2,1]-苯并硼烷及其多晶形态的方法。本发明还涉及5-(4-氰基苯氧基)-1,3-二氢-1-羟基-[2,1]-苯并硼烷的盐及其制备方法，以及它们在制备式-1纯化化合物中的应用。
• Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof
  申请人：MSN LABORATORIES PRIVATE LIMITED, R&D CENTER

  公开号：US10865217B2

  公开（公告）日：2020-12-15

  The present invention relates to process for the preparation of 5-(4-cyano phenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole represented by the following structural formula-1 and polymorphs thereof. The present invention also relates to salts of 5-(4-cyano phenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and process for their preparation and their use in the preparation of pure compound of the formula-1.

  本发明涉及以下列结构式-1表示的5-(4-氰基苯氧基)-1,3-二氢-1-羟基-[2,1]-苯并氧硼烷的制备工艺及其多晶型物。本发明还涉及 5-(4-氰基苯氧基)-1,3-二氢-1-羟基-[2,1]-苯并氧硼烷的盐及其制备工艺和它们在制备纯的式-1 化合物中的用途。
• PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF
  申请人：MSN LABORATORIES PRIVATE LIMITED, R&D CENTER

  公开号：US20200190120A1

  公开（公告）日：2020-06-18

  The present invention relates to process for the preparation of 5-(4-cyano phenoxy)- 1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole represented by the following structural formula-1 and polymorphs thereof. The present invention also relates to salts of 5-(4-cyano phenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and process for their preparation and their use in the preparation of pure compound of the formula-1.