5,8-dibromo-2,3-di(5-chloro-1H-2-pyrrolyl)quinoxaline | 828912-56-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 5,8-dibromo-2,3-di(5-chloro-1H-2-pyrrolyl)quinoxaline
• 英文别名: 5,8-Dibromo-2,3-bis(5-chloro-1H-pyrrol-2-yl)quinoxaline
• CAS: 828912-56-7
• 化学式: C₁₆H₈Br₂Cl₂N₄
• 分子量: 486.98
• InChiKey: GBRUFDOVCNCVTO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  57.4
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  三丁基(2,3-二氢噻吩并[3,4-b]-[1,4]二恶英-5-基)锡烷 、 5,8-dibromo-2,3-di(5-chloro-1H-2-pyrrolyl)quinoxaline 在 bis-triphenylphosphine-palladium(II) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 15.0h， 以33%的产率得到5,8-di(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-2,3-di(5-chloro-1H-2-pyrrolyl)quinoxaline
  参考文献：
  名称：

  Materials chemistry approach to anion-sensor design

  摘要：

  A new approach to sensing of aqueous phosphate-related anions based on chromogenic conductive polymers is demonstrated. The anion-sensor affinity can be adjusted by externally applied voltage. Introduction of p-doping to the polymers results in augmented anion sensitivity, which is ascribed to the effect of synergy between low-level p-doping in a polythiophene polymer and hydrogen bonding. The chromogenic conductive polymer films display anion-specific changes in color, conductivity, and mass upon increasing concentration of anions. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.08.060
• 作为产物：
  描述：

  1,2-二(1H-吡咯-2-基)-1,2-乙烷二酮 在 磺酰氯 、 溶剂黄146 作用下， 以 氯仿 为溶剂， 反应 29.0h， 生成 5,8-dibromo-2,3-di(5-chloro-1H-2-pyrrolyl)quinoxaline
  参考文献：
  名称：

  Materials chemistry approach to anion-sensor design

  摘要：

  A new approach to sensing of aqueous phosphate-related anions based on chromogenic conductive polymers is demonstrated. The anion-sensor affinity can be adjusted by externally applied voltage. Introduction of p-doping to the polymers results in augmented anion sensitivity, which is ascribed to the effect of synergy between low-level p-doping in a polythiophene polymer and hydrogen bonding. The chromogenic conductive polymer films display anion-specific changes in color, conductivity, and mass upon increasing concentration of anions. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.08.060

文献信息

• Materials chemistry approach to anion-sensor design
  作者：Pavel Anzenbacher、Karolina Jursikova、Dmitry Aldakov、Manuel Marquez、Radek Pohl

  DOI：10.1016/j.tet.2004.08.060

  日期：2004.11

  A new approach to sensing of aqueous phosphate-related anions based on chromogenic conductive polymers is demonstrated. The anion-sensor affinity can be adjusted by externally applied voltage. Introduction of p-doping to the polymers results in augmented anion sensitivity, which is ascribed to the effect of synergy between low-level p-doping in a polythiophene polymer and hydrogen bonding. The chromogenic conductive polymer films display anion-specific changes in color, conductivity, and mass upon increasing concentration of anions. (C) 2004 Elsevier Ltd. All rights reserved.