2,2-dimethyl-3-p-tolylpropan-1-ol | 22490-58-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2-dimethyl-3-p-tolylpropan-1-ol
• 英文别名: β.β-dimethyl-γ-p-tolyl-propyl alcohol；1-Methyl-4-(γ-oxy-β.β-dimethyl-propyl)-benzol；γ-Oxy-β.β-dimethyl-α-p-tolyl-propan；β.β-Dimethyl-γ-p-tolyl-propylalkohol；2,2-Dimethyl-3-(p-tolyl)propanol；2,2-Dimethyl-3-(4-methylphenyl)propan-1-ol
• CAS: 22490-58-0
• 化学式: C₁₂H₁₈O
• 分子量: 178.274
• InChiKey: JMPFPXGFIBHGOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-甲基氯苄 在 lithium aluminium tetrahydride 、 sodium hydride 作用下， 生成 2,2-dimethyl-3-p-tolylpropan-1-ol
  参考文献：
  名称：

  The Migration Aptitude of Substituted Benzyl vs. Methyl in Carbonium Ion Reactions of the 2,2-Dimethyl-3-aryl-1-propyl System. The Question of Alkyl Participation¹

  摘要：

  DOI：

  10.1021/ja00976a022

文献信息

• [EN] PERFUME SYSTEMS<br/>[FR] SYSTÈMES DE PARFUM
  申请人：PROCTER & GAMBLE

  公开号：WO2015148743A1

  公开（公告）日：2015-10-01

  The present application relates to perfume raw materials, perfume delivery systems and consumer products comprising such perfume raw materials and/or such perfume delivery systems, as well as processes for making and using such perfume raw materials, perfume delivery systems and consumer products. Such perfume raw materials and compositions, including the delivery systems, disclosed herein expand the perfume communities' options as such perfume raw materials can provide variations on character and such compositions can provide desired odor profiles.

  本申请涉及香水原料、香水传递系统和包含这些香水原料和/或香水传递系统的消费品，以及制造和使用这些香水原料、香水传递系统和消费品的过程。本文披露的香水原料和组合物，包括传递系统，扩展了香水社区的选择，因为这些香水原料可以提供不同的特性变化，这些组合物可以提供所需的气味特征。
• Olfactory adaption and cross-adapting agents to reduce the perception of body odors
  申请人：Symrise AG

  公开号：EP2581077A2

  公开（公告）日：2013-04-17

  Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants. Methods of making deodorant compositions are also provided wherein a cross-adapting agent, alone or in combination with other such agents, are included in an amount effective to reduce perception of malodor.

  公开的除臭剂组合物包含一种交叉适应剂，单独使用或与其他此类制剂结合使用，其用量可有效减少恶臭的感觉。此外，还公开了一种除臭剂组合物，其中包含一种交叉适应剂，单独使用或与其他此类制剂一起使用时，其用量可有效减少对不同性别体味的感知。这些方法的特点是通过施用除臭剂组合物来减少体味，其中该组合物包含一定量的交叉适应剂，可有效减少对这种气味的感知。其他方法的特点是阻断体味，包括施用除臭剂组合物，其中该组合物包含一定量的交叉适应剂，能有效占据气味受体位点，从而阻断该位点与其他气味剂的相互作用。此外，还提供了制作除臭剂组合物的方法，其中交叉适应剂单独或与其他此类制剂结合使用，其用量可有效减少恶臭的感觉。
• Olfactory adaptation and cross-adapting agents to reduce the perception of body odors
  申请人：——

  公开号：US20030152538A1

  公开（公告）日：2003-08-14

  Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants. Methods of making deodorant compositions are also provided wherein a cross-adapting agent, alone or in combination with other such agents, are included in an amount effective to reduce perception of malodor.

  公开的除臭剂组合物包含一种交叉适应剂，单独使用或与其他此类制剂结合使用，其用量可有效减少恶臭的感觉。此外，还公开了一种除臭剂组合物，其中包含一种交叉适应剂，单独使用或与其他此类制剂一起使用时，其用量可有效减少对不同性别体味的感知。这些方法的特点是通过施用除臭剂组合物来减少体味，其中该组合物包含一定量的交叉适应剂，可有效减少对这种气味的感知。其他方法的特点是阻断体味，包括施用除臭剂组合物，其中该组合物包含一定量的交叉适应剂，能有效占据气味受体位点，从而阻断该位点与其他气味剂的相互作用。此外，还提供了制作除臭剂组合物的方法，其中交叉适应剂单独或与其他此类制剂结合使用，其用量可有效减少恶臭的感觉。
• Haller; Bauer, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1911, vol. 153, p. 22
  作者：Haller、Bauer

  DOI：——

  日期：——
• EP1474095A4
  申请人：——

  公开号：EP1474095A4

  公开（公告）日：2007-11-28