N-phenyl-N'-phenylacetyl-thiourea | 72411-02-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-phenyl-N'-phenylacetyl-thiourea
• 英文别名: N-Phenyl-N'-phenylacetyl-thioharnstoff；N--N'-phenyl-thioharnstoff；N-Phenylacetyl-N'-phenyl-thioharnstoff；N-Phenyl-N'-(2-phenylacetyl)thiourea；2-phenyl-N-(phenylcarbamothioyl)acetamide
• CAS: 72411-02-0
• 化学式: C₁₅H₁₄N₂OS
• 分子量: 270.355
• InChiKey: VYSDIOYIPSIOOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  73.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-phenyl-N-phenylacetyl-thiourea 生成 N-phenyl-N'-phenylacetyl-thiourea
  参考文献：
  名称：

  Dixon; Taylor, Journal of the Chemical Society, 1907, vol. 91, p. 923

  摘要：

  DOI：

文献信息

• Reactions of thiocarbamoylaminophosphonium salts obtained from amines and the combined reagent, triphenylphosphine-thiocyanogen (TPPT): Preparation of thioureas, acylthioureas and amides.
  作者：YASUMITSU TAMURA、TOMOMI KAWASAKI、MASAHIRO ADACHI、YASUYUKI KITA

  DOI：10.1248/cpb.27.1636

  日期：——

  The thiocarbamoylaminophosphonium salt (3) obtained from an amine (1) and TPPT (2) has been shown to be a useful synthetic intermediate for the preparation of thioureas (4), amides (10) and acylthioureas (11) by treatment with water and a carboxylic acid (9). The reaction mechanism is discussed.

  从胺（1）和TPPT（2）获得的硫代氨基甲基膦盐（3）已被证明是制备硫脲（4）、酰胺（10）和酰基硫脲（11）的有用合成中间体，方法是用水和羧酸（9）进行处理。讨论了反应机制。
• Ten Ways to Reduce Detention Population
  作者：JUDGE LINDSAY G. ARTHUR

  DOI：10.1111/j.1755-6988.2001.tb00036.x

  日期：2001.1

  ABSTRACT“Juvenile detention is regularly overlooked, maligned, and misunderstood. Its embattled condition is best described as severely abused and neglected. It is underfunded, understaffed, crowded and largely ignored.”1“Detention caseloads increased 38 percent between 1987 and 1996. The increase in the number of delinquency cases handled by the courts has driven the growth in the number of juveniles in the detention system. In 1987, 1.2 million delinquency cases were disposed of in juvenile courts. By 1996, this number had risen 49 percent, to almost 1.8 million. This increase in the volume of juveniles in the justice system resulted in a 38 percent increase in the number of delinquency cases that involved the use of detention. The number of juvenile delinquency cases detained in 1996 was 89,000 more than in 1987. This has resulted in increased demand for juvenile detention bed space across the country.”2“Changes in statutes allowing more detainable offenses have significantly increased the number of youths admitted to regional detention centers.”3“Although minority youth constituted about 32 percent of the youth population in the country in 1995, they represented 68 percent of the juvenile population in secure detention…4
• SYNTHESIS OF BENZOYL-<i>N</i>-PHENYLTHIOUREAS UNDER MICROWAVE IRRADIATION AND PHASE TRANSFER CATALYSIS CONDITIONS
  作者：Lin Bai、Shengying Li、Jin-Xian Wang、Mingkai Chen

  DOI：10.1081/scc-120001519

  日期：2002.1.1

  A simple, rapid and efficient method for the synthesis of benzoyl-N-phenylthioureas under microwave irradiation is reported. The effect of microwave irradiation power, times and phase transfer catalyst on the reaction is investigated.
• Dixon; Taylor, Journal of the Chemical Society, 1907, vol. 91, p. 923
  作者：Dixon、Taylor

  DOI：——

  日期：——