5-ethyl-1-bromo-3,5-dimethyl-imidazolidine-2,4-dione | 101012-25-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 5-ethyl-1-bromo-3,5-dimethyl-imidazolidine-2,4-dione
• 英文别名: 5-Aethyl-1-brom-3,5-dimethyl-imidazolidin-2,4-dion；1-Bromo-3,5-dimethyl-5-ethylhydantoin；1-bromo-5-ethyl-3,5-dimethylimidazolidine-2,4-dione
• CAS: 101012-25-3
• 化学式: C₇H₁₁BrN₂O₂
• 分子量: 235.081
• InChiKey: YZEDHZYPKWASCK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium hydroxide 、 溴 作用下， 生成 5-ethyl-1-bromo-3,5-dimethyl-imidazolidine-2,4-dione
  参考文献：
  名称：

  Orazi et al., Anales des la Asociacion Quimica Argentina, 1957, vol. 45, p. 139,146

  摘要：

  DOI：

文献信息

• PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS
  申请人：Gilead Pharmasset LLC

  公开号：US20150361073A1

  公开（公告）日：2015-12-17

  The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.

  本公开提供了制备一种化合物的方法，该化合物的化学式如下所示：该化合物可用作抗病毒药物。本公开还提供了合成中间体化合物。
• [EN] 1-CARBAMOYLCYCLOALKYLCARBOXYLIC ACID COMPOUNDS, PROCESSES FRO MAKING AND USES THEREOF<br/>[FR] COMPOSES D'ACIDE 1-CARBAMOYLCYCLOALKYLCARBOXYLIQUE, PROCEDES DE FABRICATION ET D'UTILISATION ASSOCIES
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2005019158A1

  公开（公告）日：2005-03-03

  The invention relates to the field of pharmaceutics and more specifically to novel cycloalkylamidoacid compositions useful in the preparation of cycloalkyaminoacids and oxazolidinediones, and processes for making cycloamidoacids. Formula (1)

  该发明涉及制药领域，更具体地涉及用于制备环状氨基酸和噁唑烷二酮的新型环状烷基酰胺酸组合物，以及制备环状酰胺酸的方法。公式（1）
• [EN] PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS<br/>[FR] PROCÉDÉS DE PRÉPARATION DE COMPOSÉS ANTIVIRAUX
  申请人：GILEAD PHARMASSET LLC

  公开号：WO2015191437A1

  公开（公告）日：2015-12-17

  The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.

  本披露提供了一种制备式为的化合物的过程：它可用作抗病毒剂。该披露还提供了合成中间体化合物。
• PREPARATION OF PRASUGREL HYDROCHLORIDE
  申请人：Anumula Raghupathi Reddy

  公开号：US20130274284A1

  公开（公告）日：2013-10-17

  The present application relates to process for the preparation of prasugrel, its pharmaceutically acceptable salts, and its intermediates.

  本申请涉及一种制备prasugrel、其药用可接受盐和中间体的工艺。
• Processes for preparing antiviral compounds
  申请人：Gilead Pharmasset LLC

  公开号：US10584109B2

  公开（公告）日：2020-03-10

  The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.

  本公开提供了制备式化合物的工艺： 该化合物可用作抗病毒剂。本公开还提供了作为合成中间体的化合物。