3-(Aminomethyl)benzene-1-sulfonylfluoridehydrochloride | 2731014-02-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(Aminomethyl)benzene-1-sulfonylfluoridehydrochloride
• 英文别名: 3-(aminomethyl)benzenesulfonyl fluoride;hydrochloride
• CAS: 2731014-02-9
• 化学式: C7H9ClFNO2S
• 分子量: 225.67
• InChiKey: INTXEGSTVLONBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.23
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  68.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• ANTI-SARS-COV-2-SPIKE GLYCOPROTEIN ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS
  申请人：Regeneron Pharmaceuticals, Inc.

  公开号：EP3889177A1

  公开（公告）日：2021-10-06

  The present disclosure provides antibodies and antigen-binding fragments thereof that bind specifically to a coronavirus spike protein and methods of using such antibodies and fragments for treating or preventing viral infections (e.g., coronavirus infections).

  本公开提供了与冠状病毒尖峰蛋白特异性结合的抗体及其抗原结合片段，以及使用这种抗体和片段治疗或预防病毒感染（如冠状病毒感染）的方法。
• Anti-SARS-CoV-2-Spike glycoprotein antibodies and antigen-binding fragments
  申请人：Regeneron Pharmaceuticals, Inc.

  公开号：US10975139B1

  公开（公告）日：2021-04-13

  The present disclosure provides antibodies and antigen-binding fragments thereof that bind specifically to a coronavirus spike protein and methods of using such antibodies and fragments for treating or preventing viral infections (e.g., coronavirus infections).

  本公开提供了与冠状病毒尖峰蛋白特异性结合的抗体及其抗原结合片段，以及使用这种抗体和片段治疗或预防病毒感染（如冠状病毒感染）的方法。
• ANTI-TMPRSS2 ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS
  申请人：Regeneron Pharmaceuticals, Inc.

  公开号：EP3638698A1

  公开（公告）日：2020-04-22
• Methods Of Identifying Subjects Having An Increased Risk Of Developing A Coronavirus Infection And Treatment Thereof
  申请人：Regeneron Pharmaceuticals, Inc.

  公开号：US20220177982A1

  公开（公告）日：2022-06-09

  Methods of treating subjects having a coronavirus infection, and methods of identifying subjects having an increased risk of a coronavirus infection are provided herein.
• [EN] ANTI-TMPRSS2 ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS<br/>[FR] ANTICORPS ANTI-TMPRSS2 ET FRAGMENTS DE LIAISON À L'ANTIGÈNE
  申请人：REGENERON PHARMA

  公开号：WO2019147831A1

  公开（公告）日：2019-08-01

  The present invention includes an antibody or antigen-binding fragment thereof that binds specifically to TMPRSS2 and methods of using such antibodies and fragments for treating or preventing viral infections (e.g., influenza virus infections).