2-(3-Methyl-5-phenylpyrazol-1-yl)pyridine | 80884-12-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-(3-Methyl-5-phenylpyrazol-1-yl)pyridine
• CAS: 80884-12-4
• 化学式: C₁₅H₁₃N₃
• 分子量: 235.288
• InChiKey: WJLSLUVTSUISFR-UHFFFAOYSA-N

物化性质

• 沸点：
  402.2±30.0 °C(Predicted)
• 密度：
  1.13±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-肼吡啶 在 盐酸 、 溴 作用下， 以 乙醇 、 水 为溶剂， 反应 2.0h， 生成 2-(3-Methyl-5-phenylpyrazol-1-yl)pyridine
  参考文献：
  名称：

  Feid-Allah, Pharmazie, 1981, vol. 36, # 11, p. 754 - 756

  摘要：

  DOI：

文献信息

• Layered Zirconium Sulfophenyl Phosphonate as Heterogeneous Catalyst in the Synthesis of Pyrazoles and 4,5,6,7-Tetrahydro-1(2)<i>H</i>-indazoles
  作者：Massimo Curini、Ornelio Rosati、Valerio Campagna、Francesca Montanari、Giancarlo Cravotto、Mauro Boccalini

  DOI：10.1055/s-2005-921904

  日期：——

  Pyrazoles and tetrahydroindazoles may be prepared by condensation of 1,3-diones and hydrazines under layered zirconium sulfophenyl phosphonate catalysis, in solvent-free conditions.

  吡唑和四氢吲哒唑可以通过在无溶剂条件下，层状锆磺苯膦酸盐催化剂的作用下，由1,3-二酮和肼缩合制备得到。
• SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES
  申请人：Bayer Aktiengesellschaft

  公开号：US20200390100A1

  公开（公告）日：2020-12-17

  The present invention relates to substituted N-heterocyclyl- and N-heteroaryltetrahydropyrimidinones of the general formula (I) or salts thereof, where the radicals in the general formula (I) correspond to the definitions given in the description, and to the use thereof as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants.

  本发明涉及通式（I）或其盐的取代N-杂环烷基和N-杂芳基四氢嘧啶酮，其中通式（I）中的基团对应于描述中给出的定义，并将其用作除草剂，特别是用于控制作物中的阔叶杂草和/或杂草草，并/或作为植物生长调节剂，以影响作物的生长。
• ETHEREAL OXYGEN ATOM-CONTAINING PERFLUOROALKYL GROUP-SUBSTITUTED PYRAZOLE RING COMPOUND AND METHOD FOR ITS PRODUCTION
  申请人：ASAHI GLASS COMPANY, LIMITED

  公开号：US20160295864A1

  公开（公告）日：2016-10-13

  To provide a pyrazole derivative having a superior fluorinated substituent, which is useful for pharmaceutical products or agricultural chemicals having pharmacological activities, and a method for its production. A compound represented by the following formula (A), wherein R f is a C 2-19 perfluoroalkyl group having ethereal oxygen atom(s) inserted between carbon-carbon atoms of the group, and the total number of carbon atoms and oxygen atoms in R f being from 3 to 20, one of Q 1 and Q 2 is a hydrogen atom, and the other is a phenyl group, or a phenyl group in which at least one hydrogen atom in the phenyl group is each independently substituted by a halogen atom, and one of A 1 and A 2 is a nitrogen atom, and the other is a nitrogen atom to which R 1 is bonded.

  提供一种具有优越氟代取代基的吡唑衍生物，适用于具有药理活性的制药产品或农用化学品，并提供其生产方法。所述化合物由以下式（A）表示，其中Rf是具有乙醚氧原子插入其碳-碳原子之间的C2-19全氟烷基基团，Rf中的碳原子和氧原子的总数为3至20，Q1和Q2中的一个是氢原子，另一个是苯基，或者至少一个苯基中的氢原子各自独立地被卤素原子取代，A1和A2中的一个是氮原子，另一个是与R1键合的氮原子。
• Regioselective synthesis of multisubstituted pyrazoles via cyclocondensation of β-thioalkyl-α,β-unsaturated ketones with hydrazines
  作者：Weiwei Jin、Haifeng Yu、Zhengkun Yu

  DOI：10.1016/j.tetlet.2011.08.168

  日期：2011.11

  Multisubstituted pyrazoles were efficiently synthesized by cyclocondensation of beta-thioalkyl-alpha,beta-unsaturated ketones with hydrazines under relatively mild conditions. A one-pot synthetic protocol through tandem Liebeskind-Srogl cross-coupling/cyclocondensation using alpha-oxo ketene dithioacetals as the starting materials was also realized for the same purpose. (C) 2011 Elsevier Ltd. All rights reserved.
• [DE] SUBSTITUIERTE HETEROARYLPYRROLONE SOWIE DEREN SALZE UND IHRE VERWENDUNG ALS HERBIZIDE WIRKSTOFFE<br/>[EN] SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES<br/>[FR] HÉTÉROARYLPYRROLONES SUBSTITUÉES ET LEURS SELS ET LEUR UTILISATION COMME AGENTS HERBICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2018114596A1

  公开（公告）日：2018-06-28

  Die vorliegende Erfindung betrifft substituierte Heteroarylpyrrolone der allgemeinen Formel (I) oder deren Salz, wobei die Reste in der allgemeinen Formel (I) den in der Beschreibung gegebenen Definitionen entsprechen, sowie deren Verwendung als Herbizide, inbesondere zur Bekämpfung von Unkräutern und/oder Ungräsern in Nutzpflanzenkulturen und/oder als Pflanzenwachstumsregulatoren zur Beeinflussung des Wachstums von Nutzpflanzenkulturen.