3-(2-chloro-6-fluorophenyl)-1-[4-(3-chloro-5-trifluoromethylpyridin-2-yloxymethyl)phenyl]-5-methyl-1H-1,2,4-triazole | 475153-92-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-(2-chloro-6-fluorophenyl)-1-[4-(3-chloro-5-trifluoromethylpyridin-2-yloxymethyl)phenyl]-5-methyl-1H-1,2,4-triazole
• 英文别名: 3-chloro-2-[[4-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2,4-triazol-1-yl]phenyl]methoxy]-5-(trifluoromethyl)pyridine
• CAS: 475153-92-5
• 化学式: C₂₂H₁₄Cl₂F₄N₄O
• 分子量: 497.279
• InChiKey: FUSIWMIIFCUTBH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  33
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  52.8
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  3-chloro-2-methanesulfonyl-5-trifluoromethylpyridine 、 4-[3-(2-chloro-6-fluorophenyl)-5-methyl-1H-1,2,4-triazol-1-yl]phenylmethanol 在 sodium hydride 作用下， 以 DMF (N,N-dimethyl-formamide) 为溶剂， 反应 55.0h， 以46%的产率得到3-(2-chloro-6-fluorophenyl)-1-[4-(3-chloro-5-trifluoromethylpyridin-2-yloxymethyl)phenyl]-5-methyl-1H-1,2,4-triazole
  参考文献：
  名称：

  EP1386915

  摘要：

  公开号：

文献信息

• Azole compounds, process for preparation of the same and use thereof
  申请人：Itoh Shigeyuki

  公开号：US20050009834A1

  公开（公告）日：2005-01-13

  The invention provides novel azole compounds useful as pest controllers and novel pest controllers containing the compounds as the active ingredient. The invention discloses azole compounds represented by the following general formula, a production process for preparation of the compounds, and use thereof as insecticides or acaricides: wherein X 1 to X 5 and Z 1 to Z 4 are each N, C—H, C-halogen, C-alkyl, or the like; Y 1 and Y 2 are each N or CH, with the proviso that both Y 1 and Y 2 must not be CH; A is a single bond, O, or the like; Ar is an optionally substituted aromatic residue; B is halogeno, alkyl, or the like; R 1 is H, halogeno, alkyl, or the like; R 2 and R 3 are each H, alkyl, or the like; m is 0 to 2; and n is 0 or 1.

  该发明提供了新型的唑类化合物，可用作害虫控制剂，以及含有该化合物作为活性成分的新型害虫控制剂。该发明揭示了由以下通式表示的唑类化合物，制备该化合物的生产工艺，并将其用作杀虫剂或螨虫剂：其中X1至X5和Z1至Z4均为N、C—H、C-卤素、C-烷基或类似物；Y1和Y2均为N或CH，但必须满足Y1和Y2不能同时为CH；A为单键、O或类似物；Ar为可选取代的芳香残基；B为卤素、烷基或类似物；R1为H、卤素、烷基或类似物；R2和R3均为H、烷基或类似物；m为0至2；n为0或1。
• AZOLE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF
  申请人：Sumitomo Chemical Takeda Agro Company, Limited

  公开号：EP1386915A1

  公开（公告）日：2004-02-04

  The invention provides novel azole compounds useful as pest controllers and novel pest controllers containing the compounds as the active ingredient. The invention discloses azole compounds represented by the following general formula, a production process for preparation of the compounds, and use thereof as insecticides or acaricides: wherein X1 to X5 and Z1 to Z4 are each N, C-H, C-halogen, C-alkyl, or the like; Y1 and Y2 are each N or CH, with the proviso that both Y1 and Y2 must not be CH; A is a single bond, O, or the like; Ar is an optionally substituted aromatic residue; B is halogeno, alkyl, or the like; R1 is H, halogeno, alkyl, or the like; R2 and R3 are each H, alkyl, or the like; m is 0 to 2; and n is 0 or 1.

  本发明提供了可用作害虫控制剂的新型唑类化合物，以及以该化合物为活性成分的新型害虫控制剂。本发明公开了由以下通式表示的唑类化合物、制备该化合物的生产工艺及其作为杀虫剂或杀螨剂的用途： 其中X1至X5和Z1至Z4各自为N、C-H、C-卤素、C-烷基或类似物；Y1和Y2各自为N或CH，但Y1和Y2均不得为CH；A为单键、O或类似物；Ar为任选取代的芳香残基；B为卤素、烷基或类似物；R1为H、卤素、烷基或类似物；R2和R3各自为H、烷基或类似物；m为0至2；n为0或1。