1,3-Bis-(dihydroxymethylphosphino)-propan | 18721-53-4

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: 1,3-Bis-(dihydroxymethylphosphino)-propan
• 英文别名: [3-[Bis(hydroxymethyl)phosphanyl]propyl-(hydroxymethyl)phosphanyl]methanol
• CAS: 18721-53-4
• 化学式: C₇H₁₈O₄P₂
• 分子量: 228.165
• InChiKey: PXMMSQLOWJYXAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.3
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  palladium diacetate 、 1,3-Bis-(dihydroxymethylphosphino)-propan 以 乙醇 、 乙腈 为溶剂， 生成
  参考文献：
  名称：

  阳离子二磷钯（II）配合物在烯烃/ CO在有机溶剂和水中共聚中的催化活性取决于膦配体上烷基链的长度

  摘要：

  一系列双膦配体CH 2（CH 2 PR 2）2（1a – x）（a – g：R =（CH 2）n OH，n = 1，3-8; h – k：R =（CH 2）n CH（CH 2 OH）2，n = 3–6；l – u：R = C n H 2 n +1，n = 1–8，10，14; v – x：R = CH（CH 3通过相应的1-烯烃的加氢磷酸化反应制备具有不同极性官能团的）2，（CH 2）2 CH（CH 3）2，（CH 2）3 CH（CH 3）2（方案1）。 H 2 P（CH 2）3 PH 2或格氏试剂与Cl 2 P（CH 2）3 PCl 2的反应。水溶性钯络合物[（R 2 P（CH 2）3 PR 2）Pd（OAc）2 ]（2a - k）是通过Pd（OAc）2与配体1a - k在乙醇-乙腈中的反应获得的。用1l – x处理PdCl 2（NCC 6 H 5）2得到二氯钯（II）络合物[（R 2 P（CH

  DOI：

  10.1016/s0022-328x(00)00154-6

文献信息

• Purified sulfonated organophosphorus compounds and catalysis of organic reactions therewith
  申请人：——

  公开号：US20020016497A1

  公开（公告）日：2002-02-07

  Water-soluble sulfonated organophosphorus compounds are purified by at least partially removing contaminating sulfite values therefrom, by decreasing the pH of a solution of such sulfonated organophosphorus compounds to a value of less than or equal to 4, and maintaining the pH of the solution at this value of 4 or less for such period of time as to reduce the weight concentration of sulfite in the solution to less than 100 ppm; the organophosphorus compounds thus purified are well suited for the two-phase cocatalysis of a wide variety of organic reactions.

  将水溶性磺化有机磷化合物溶液的 pH 值降至小于或等于 4，并将该溶液的 pH 值保持在 4 或 4 以下一段时间，以将溶液中亚硫酸盐的重量浓度降至低于 100 ppm，从而至少部分去除其中的亚硫酸盐污染值，从而提纯水溶性磺化有机磷化合物；这样提纯的有机磷化合物非常适合用于多种有机反应的两相催化。
• Production of nitriles via hydrocyanation of ethylenically unsaturated organic compounds
  申请人：——

  公开号：US20020022736A1

  公开（公告）日：2002-02-21

  Ethylenically unsaturated organic compounds, for example diolefins, olefinic nitrites and monoolefins, are noncontaminatingly hydrocyanated into corresponding nitrites by (a) reacting such ethylenically unsaturated organic compounds with hydrogen cyanide in the presence of an aqueous solution containing a catalytically effective amount of a catalyst which comprises at least one nickel compound and at least one water-soluble phosphine, (b) thereafter separating the organic phase from the aqueous phase which result, the separated aqueous phase comprising a solid phase formed during hydrocyanation, and (c) thence treating the separated aqueous phase, or a solid phase removed therefrom, with hydrogen cyanide to thus at least partially dissolve said solid phase contained therein or removed therefrom.

  乙烯基不饱和有机化合物，例如二烯烃、烯烃亚硝酸盐和单烯烃，可通过以下方法无污染地加氢氰化成相应的亚硝酸盐：(a) 在含有催化有效量催化剂的水溶液中，使这些乙烯基不饱和有机化合物与氰化氢反应，该催化剂包括至少一种镍化合物和至少一种水溶性膦、(c) 然后用氰化氢处理分离出的水相或从中除去的固相，使其中所含或从中除去的固相至少部分溶解。
• Production of hydrocyanation catalysts
  申请人：——

  公开号：US20020026066A1

  公开（公告）日：2002-02-28

  Hydrocyanation catalysts comprising aqueous solutions of at least one water-soluble phosphine and nickel values, well suited for the hydrocyanation of ethylenically unsaturated organic compounds such as diolefins, olefinic nitrites and monolefins, are produced by (a) admixing an aqueous solution of such at least one water-soluble phosphine with a nickel hydroxide, (b) adding hydrogen cyanide or a compound which generates hydrogen cyanide to the mixture thus formed, (c) stirring the resulting mixture until the nickel values have at least partially dissolved, and (d) reducing at least a portion of said nickel values having an oxidation state of greater than zero to the zero oxidation state.

  由至少一种水溶性膦和镍值的水溶液组成的氢氰化催化剂，非常适用于乙烯基不饱和有机化合物如二烯烃、烯烃亚硝酸盐和单烯烃的氢氰化，其生产方法是：(a) 将至少一种水溶性膦的水溶液与氢氧化镍混合、(b) 向由此形成的混合物中加入氰化氢或可生成氰化氢的化合物， (c) 搅拌所得混合物，直至镍值至少部分溶解， (d) 将氧化态大于零的上述镍值中的至少一部分还原至零氧化态。
• PROCEDE D'HYDROCYANATION DE COMPOSES ORGANIQUES A INSATURATION ETHYLENIQUE
  申请人：RHODIA POLYAMIDE INTERMEDIATES

  公开号：EP0854858B1

  公开（公告）日：2001-06-13
• PROCEDE DE PREPARATION PAR HYDROGENATION DE CATALYSEURS A BASE DE METAL DE TRANSITION ET DE PHOSPHINE
  申请人：RHODIA FIBER & RESIN INTERMEDIATES

  公开号：EP0876214A1

  公开（公告）日：1998-11-11