(4-(methyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone | 42875-13-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-(methyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone
• 英文别名: (4-(Methyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanon；(4-Methylphenyl)-(4-prop-2-ynoxyphenyl)methanone
• CAS: 42875-13-8
• 化学式: C₁₇H₁₄O₂
• 分子量: 250.297
• InChiKey: UKVMHZFUWSBKGN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT<br/>[FR] ANALOGUES DE NUCLÉOSIDES ET DE NUCLÉOTIDES PORTANT UN CENTRE STÉRÉOGÈNE TOUT CARBONE QUATERNAIRE EN POSITION 2' ET PROCÉDÉS D'UTILISATION EN TANT QU'AGENT CARDIOPROTECTEUR
  申请人：LCB PHARMA INC

  公开号：WO2018049534A1

  公开（公告）日：2018-03-22

  Nucleoside and nucleotide analogues that can be used as cardioprotective agents are provided. The nucleosides and nucleotide analogues comprise tetrahydrofuranyl or tetrahydrothienyl moieties with quaternary stereogenic all-carbon centers at the 2' position and a phosphonate ester at the 5' position.

  提供可用作心脏保护剂的核苷和核苷酸类似物。这些核苷和核苷酸类似物包括在2'位置具有四氢呋喃基或四氢噻吩基的四面体立体异构所有碳中心，以及在5'位置具有磷酸酯基。
• BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES
  申请人：Alfa Instruments S.r.l.

  公开号：EP3692101B1

  公开（公告）日：2022-01-12
• BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE
  申请人：Sadar Marianne D.

  公开号：US20130109758A1

  公开（公告）日：2013-05-02

  This invention provides compounds having a structure of Formula (I). Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.
• [EN] BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES<br/>[FR] DÉRIVÉS DE COLORANT BLEU BRILLANT (BBG) ET COMPOSITIONS DE COLORATION LES COMPRENANT POUR COLORER SÉLECTIVEMENT DES SUBSTRATS BIOLOGIQUES
  申请人：ALFA INSTR S R L

  公开号：WO2019068935A1

  公开（公告）日：2019-04-11

  The present invention relates to dye molecules and to staining compositions comprising said dye molecules that are particularly suitable for selectively staining biological substrates, such as structures in the posterior eye segment and proteins. Said dye molecules may be used in ophthalmic surgery to help the surgeon to visualize structures in the posterior eye structures as well as in protein assays to determine one or more analytical parameter of a protein. The dye molecules have the following structure (I) wherein X represents an organic or inorganic cation; and R1 represents a substituted or unsubstituted benzyl group. The present invention relates also to a new method for synthetizing dye molecules.