tert-butyl(3-methoxycarbonylphenyl)phosphine | 146061-77-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tert-butyl(3-methoxycarbonylphenyl)phosphine
• 英文别名: Methyl 3-tert-butylphosphanylbenzoate
• CAS: 146061-77-0
• 化学式: C₁₂H₁₇O₂P
• 分子量: 224.24
• InChiKey: ZLMBAGATUHVLSZ-UHFFFAOYSA-N

物化性质

• 沸点：
  315.5±25.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  tert-butyl(3-methoxycarbonylphenyl)phosphine 在 air 作用下， 以 苯 为溶剂， 反应 1.5h， 以83%的产率得到tert-butyl(3-methoxycarbonylphenyl)phosphonous acid
  参考文献：
  名称：

  Veits; Karlstedt; Foss, Russian Journal of Organic Chemistry, 1998, vol. 34, # 4, p. 525 - 529

  摘要：

  DOI：
• 作为产物：
  描述：

  3-溴苯甲酸甲酯 、 tert-butyl(trimethylsilyl)phosphine 在 bis-triphenylphosphine-palladium(II) chloride 作用下， 反应 10.0h， 以84%的产率得到tert-butyl(3-methoxycarbonylphenyl)phosphine
  参考文献：
  名称：

  Veits; Karlstedt; Foss, Russian Journal of Organic Chemistry, 1998, vol. 34, # 4, p. 525 - 529

  摘要：

  DOI：

文献信息

• ortho-palladated α-phenylalkylamines for enantiomeric purity determination of monodentate P∗-chiral phosphines
  作者：V.V. Dunina、L.G. Kuz'mina、M.Yu. Kazakova、Yu.K. Grishin、Yu.A. Veits、E.I. Kazakova

  DOI：10.1016/s0957-4166(97)00300-5

  日期：1997.8

  Three ortho-palladated complexes were tested as chiral derivatizing agents for enantiomeric excess determination of monodentate P-*-chiral phosphines by P-31 NMR analysis. The complexes containing a bulky substituent at the alpha-C-* - 1e or an N-*-stereocentre 1d are shown to be more efficient as compared to known N-achiral alpha-methyl substituted analogues. The structure and stereochemistry of the new dimeric complex (S-c)-1e was established by X-ray analysis. (C) 1997 Published by Elsevier Science Ltd.
• Synthesis of asymmetric secondary phosphines by the cross coupling of arylhalides with silylphosphines
  作者：I. P. Beletskaya、Yu. A. Veits、V. A. Leksunkin、V. L. Foss

  DOI：10.1007/bf00864195

  日期：1992.7

  The cross coupling of aryl halides with alkyl(trimethylsilyl)phosphines catalyzed by zero-valent palladium complexes yields secondary alkylarylphosphoranes containing both electron-donor and electron-withdrawing substituents in the aromatic ring. The reversible disproportionation of alkylsilylphosphines to give AlkPH2 and AlkP(SiMe3)2 was observed for the first time during this reaction. This disproportionation does not affect the yield of AlkArPH, which are formed in virtually quantitative yield, due to the high rate of cross coupling with AlkP(SiMe3)H2 and the reversibility of the disproportionation process.