tetrahydropyranyl chloride | 132628-42-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: tetrahydropyranyl chloride
• 英文别名: (S)-2-Chlorotetrahydro-2H-pyran；(2S)-2-chlorooxane
• CAS: 132628-42-3
• 化学式: C₅H₉ClO
• 分子量: 120.579
• InChiKey: QRECIVPUECYDDM-RXMQYKEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  钾[锰(五羰基)] 、 tetrahydropyranyl chloride 以 乙醚 为溶剂， 以97%的产率得到2-manganese pentacarbonyl tetrahydropyran
  参考文献：
  名称：

  Glycosylmanganese pentacarbonyl complexes: an organomanganese-based approach to the synthesis of C-glycosyl derivatives

  摘要：

  Preparation, structure and reactions of glycosylmanganese pentacarbonyl complexes are discussed. Anomerically pure complexes of pyranosyl and furanosyl complexes were prepared in excellent yield. The conformations of the anomeric glucosyl and mannosyl complexes were derived from detailed analysis of their 1D and 2D H-1- and C-13-NMR spectra including NOE data. The complexes are further characterized by Mn-55-NMR chemical shifts and Mn-55, C-13 one-bond coupling constants. These compounds undergo various migratory insertion reactions resulting in formation of C-glycosyl derivatives. Applications of this technology to the synthesis of C-glycosyl and C-aryl glycosidic systems are discussed. (C) 2000 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(99)00431-3