(-)-2-amino-1-(2,5-dimethylphenyl)-1-propanol hydrochloride | 102994-21-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (-)-2-amino-1-(2,5-dimethylphenyl)-1-propanol hydrochloride
• 英文别名: 2-Amino-1-(2,5-dimethylphenyl)propan-1-ol;hydrochloride
• CAS: 102994-21-8
• 化学式: C₁₁H₁₇NO*ClH
• 分子量: 215.723
• InChiKey: YELZOEGABBRADC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.11
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  46.2
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• An optically active borane complex and a method for producing an optically active alcohol derivative by the use thereof
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0171175A1

  公开（公告）日：1986-02-12

  An optically active borane complex represented by the general formula, wherein R1 represents an aryl group, R2 represents an alkyl group and a mark * means an asymmetric carbon, is capable of producing optically active alcohol derivatives by the reduction of prochiral ketones with the borane complex. The optically active alcohol derivative is useful for fungicides, herbicides or plant growth regulators.

  由通式表示的光学活性硼烷络合物、 其中 R1 代表芳基，R2 代表烷基，标记 * 表示不对称碳，通过用硼烷络合物还原原手性酮，可生产出光学活性醇衍生物。光学活性醇衍生物可用于杀真菌剂、除草剂或植物生长调节剂。
• Process for producing optically active alcohol
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0381434A1

  公开（公告）日：1990-08-08

  A process for producing an optically active alcohol of the formula [R⁴ and R⁵ are different and each is a lower alkyl group, an aryl group, and aralkyl group or a 2-substituted-1-­triazoleethylene group represented by the general formula (III) (R⁶ is a halogen- or haloalkyl-substituted or unsubstituted phenyl group or a cycloalkyl group)] comprises allowing (A) an optically active amino alcohol represented by the general formula (I) (R¹ is an aryl group, R² is a lower alkyl group, R³ is a hydrogen atom or a lower alkyl group, and the carbon atoms having a mark * are each an asymmetric carbon atom) and an acid, or a salt of the optically active amino alcohol (I) and an acid, (B) a metal borohydride, and (C) at least one of water, sulfides, cyclic ethers and ethers of mono alcohols to react with a prochiral ketone represented by the general formula (II) [R⁴ and R⁵ are as defined above].

  一种生产式如下的光学活性醇的工艺 [R⁴和R⁵是不同的，且各自是由通式(III)代表的低级烷基、芳基、芳烷基或 2-取代的-1-三唑乙烯基团 (R⁶为卤素或卤代烷基取代或未取代的苯基或环烷基）]包括允许 (A) 由通式(I)代表的光学活性氨基醇 (R¹为芳基，R²为低级烷基，R³为氢原子或低级烷基，带有标记*的碳原子均为不对称碳原子)和酸，或光学活性氨基醇(I)和酸的盐、 (B) 金属硼氢化物，以及 (C) 水、硫化物、环醚和单醇醚中的至少一种 与下列物质反应 与通式 (II) 所代表的手性酮反应 [R⁴ 和 R⁵ 如上定义]。
• ASYMMETRICALLY MODIFIED BORON HYDRIDE COMPOUNDS, PROCESS FOR ITS PREPARATION, AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOL DERIVATIVE USING SAME
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0142566B1

  公开（公告）日：1989-08-23
• US4749809A
  申请人：——

  公开号：US4749809A

  公开（公告）日：1988-06-07
• US4760149A
  申请人：——

  公开号：US4760149A

  公开（公告）日：1988-07-26