(1R)-1,9,11,11,12,12-hexamethyl-1,2,3,4,6,7,8,9-octahydro-1r,4c;6t,9t-dimethano-phenazine | 916658-88-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: (1R)-1,9,11,11,12,12-hexamethyl-1,2,3,4,6,7,8,9-octahydro-1r,4c;6t,9t-dimethano-phenazine
• 英文别名: (1R)-1,9,11,11,12,12-Hexamethyl-1,2,3,4,6,7,8,9-octahydro-1r,4r;6t,9t-dimethano-phenazin；(1R)-1,9,11,11,12,12-Hexamethyl-1,2,3,4,6,7,8,9-octahydro-1r,4c;6t,9t-dimethano-phenazin；(1R,5R,8S,12S)-1,5,15,15,16,16-hexamethyl-3,10-diazapentacyclo[10.2.1.15,8.02,11.04,9]hexadeca-2,4(9),10-triene
• CAS: 916658-88-3
• 化学式: C₂₀H₂₈N₂
• 分子量: 296.456
• InChiKey: AQKGLAJGQUIHSJ-ZDEMKHDWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  22
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (1R)-1,9,11,11,12,12-hexamethyl-1,2,3,4,6,7,8,9-octahydro-1r,4c;6t,9t-dimethano-phenazine 、 水 、 silver nitrate 以 甲醇 、 丙酮 为溶剂， 以30%的产率得到
  参考文献：
  名称：

  Chiral heterocyclic ligands. XIV. Control of directionality in silver coordination polymers through ligand design

  摘要：

  衍生自 (+)-樟脑的四种 C2-对称纯手性配体被证明可产生直链和梯形银配位聚合物，其中方向性和极化可以通过配体设计中的细微差异来控制。

  DOI：

  10.1039/b611622c
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 (1R)-1,9,11,11,12,12-hexamethyl-1,2,3,4,6,7,8,9-octahydro-1r,4c;6t,9t-dimethano-phenazine
  参考文献：
  名称：

  欧盟经济研究基金会巴恩·奥夫·坎佩尔奇农二世（Bain auf Campherchinon II）

  摘要：

  DOI：

  10.1002/hlca.193702001153

文献信息

• Utilizing terpene derivatives in the synthesis of annulated terpene-imidazoles with application in the nitroaldol reaction
  作者：Jiří Kulhánek、Filip Bureš、Petr Šimon、W. Bernd Schweizer

  DOI：10.1016/j.tetasy.2008.10.026

  日期：2008.11

  Two classes of terpene derivatives (diketones and monoximes) were condensed into annulated terpeneimidazoles using two general methods. Method A, involving the condensation of terpene diketones and aldehydes, gave lower yields than Method B, which employed terpene monoximes and amines. The mechanism of Method B is discussed. Using both methods, overall 11 new imidazole ligands were synthesized and fully characterized. The molecular structures of the side product 16 and intermediate 4b were also characterized by X-ray analysis. Regarding la, N-methylation and subsequent ortho-lithiation and quenching with diphenylphosphinechloride were proven. The synthesized ligands were tested in the Henry reaction providing reaction times 24-72 h and enantioselectivities up to 32% especially for the pyridine 2-substituted ligands 1c, 2c, 3b and N,P-ligand 17. (C) 2008 Elsevier Ltd. All rights reserved.
• Über die Einwirkung primärer Basen auf Campherchinon und die Bildung von Monomethyl-amido-epicampher
  作者：Hans Rupe、Henri Martin

  DOI：10.1002/hlca.193401701151

  日期：——
• de la Morena; Marquez, Anales de la Real Sociedad Espanola de Fisica y Quimica, 1958, vol. <B> 54, p. 161,164
  作者：de la Morena、Marquez

  DOI：——

  日期：——
• de la Morena Calvet; Marquez Archilla, Anales de la Real Sociedad Espanola de Fisica y Quimica, 1958, vol. <B> 54, p. 161,164
  作者：de la Morena Calvet、Marquez Archilla

  DOI：——

  日期：——