3-N,3-N,11-N,11-N-tetraethyl-2,4,10,12-tetraoxa-3,11-diphosphatricyclo[11.3.1.15,9]octadeca-1(17),5(18),6,8,13,15-hexaene-3,11-diamine | 244217-61-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-N,3-N,11-N,11-N-tetraethyl-2,4,10,12-tetraoxa-3,11-diphosphatricyclo[11.3.1.15,9]octadeca-1(17),5(18),6,8,13,15-hexaene-3,11-diamine
• CAS: 244217-61-6
• 化学式: C₂₀H₂₈N₂O₄P₂
• 分子量: 422.401
• InChiKey: HPYSOHQUOTZPSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  59
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3-N,3-N,11-N,11-N-tetraethyl-2,4,10,12-tetraoxa-3,11-diphosphatricyclo[11.3.1.15,9]octadeca-1(17),5(18),6,8,13,15-hexaene-3,11-diamine 在 双氧水 、 尿素 作用下， 以 苯 为溶剂， 反应 24.0h， 以75%的产率得到N3,N3,N11,N11-tetraethyl-2,4,10,11-tetraoxa-3λ⁵,11λ⁵-diphosphatricyclo[11.3.1.1^5,9]octadeca-1(16),5,7,9(18),13(17),14-hexaene-3,11-diamine 3,11-dioxide
  参考文献：
  名称：

  Nifant'ev, E. E.; Rasadkina, E. N.; Yankovich, I. V., Russian Journal of General Chemistry, 1999, vol. 69, # 1, p. 32 - 38

  摘要：

  DOI：
• 作为产物：
  描述：

  间苯二酚 以 1,4-二氧六环 、 二氯甲烷 、 乙腈 为溶剂， 反应 150.0h， 生成 3-N,3-N,11-N,11-N-tetraethyl-2,4,10,12-tetraoxa-3,11-diphosphatricyclo[11.3.1.15,9]octadeca-1(17),5(18),6,8,13,15-hexaene-3,11-diamine
  参考文献：
  名称：

  Phosphomacrocyclic systems based on 2,2′-dihydroxy-1,1′-dinaphtylmethane

  摘要：

  For the first time phosphomacrocyclic systems were synthesized based on 2,2'-dihydroxy-1,1'-dinaphthylmethane, other aromatic diols, and phosphorous hexaethyltriamide. Spontaneous transformation of the obtained macrocycles into the more stable 1,3,2-dioxaphosphacyn and cyclobisamidophosphite was established.

  DOI：

  10.1134/s1070363210050099

文献信息

• Phosphorylation of 1,4-bis(hydroxymethyl)benzene with trivalent phosphorus derivatives
  作者：P. V. Slitikov、V. A. Bogoyavlenskii、E. N. Rasadkina、E. E. Nifant’ev

  DOI：10.1134/s1070363207060126

  日期：2007.6

  Phosphorylation of 1,4-bis(hydroxymethyl)benzene with complete phosphorous acid amides and phenyl phosphorodichloridite is studied. Some phosphorus-containing linear systems, the phosphamacrocycle precursors, are synthesized. The possibility of synthesis of phosphamacrocyclic systems based on 1,4-bis(hydroxymethyl)benzene is considered; it was shown that this compound does not tend to form macrocycles.
• Dismutation of arylene phosphorodiamidites: Specific features and aspects of preparative use
  作者：E. N. Rasadkina、P. V. Slitikov、E. E. Nifant’ev

  DOI：10.1134/s1070363206020046

  日期：2006.2

  The dismutation ofarylene phosphorodiamidites derived from the simplest phenols and naphthols and of their dibasic analogs was studied. The main regular trends of this process and the limits of its synthetic applicability were determined.
• Dismutation of Bisphosphorylated Aromatic Diols
  作者：Edward E. Nifantyev、Elena N. Rasadkina、Pavel V. Slitikov、Larisa K. Vasyanina

  DOI：10.1080/104265090517244

  日期：2005.2

  The first study of the dismutation of aromatic diol bisdiantidophosphites has been performed. Derivatives of condensed aromatic systems dismutate more rapidly than their mononuclear analogues. Amide derivatives with aliphatic substituents at the nitrogen atom undergo dismutation more readily than their heterocyclic analogues. In methylene chloride, the process proceeded most rapidly regardless of the aromatic component and the substititent at the phosphorus atom. Apolar solvents (benzene and diethyl ether) did not favor the dismutation. Temperature had no effect oil the time of dismutation, and a catalyst decreased it by a factor of 1.5-2.