1,2,4,5-benzenetetracarboxylic acid dihydrate | 6151-22-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,2,4,5-benzenetetracarboxylic acid dihydrate
• 英文别名: benzene-1,2,4,5-tetracarboxylic acid ; dihydrate；[H4Btec*2H2O](n)；Benzol-1,2,4,5-tetracarbonsaeure; Dihydrat；pyromellitic acid dihydrate；Pyromellitic acid hydrate；benzene-1,2,4,5-tetracarboxylic acid;hydrate
• CAS: 6151-22-0；76532-02-0；83454-02-8
• 化学式: C₁₀H₆O₈*2H₂O
• 分子量: 290.183
• InChiKey: SATNOJUQGNADGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.35
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  150
• 氢给体数：
  5
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  cobalt(II) chloride hexahydrate 、 水 、 1,2,4,5-benzenetetracarboxylic acid dihydrate 在 (NH₄)Mo₇O₂₄*6H₂O 作用下， 以 水 为溶剂， 以20%的产率得到hexaaquacobalt(II) dihydrogen 1,2,4,5-benzenetetracarboxylate
  参考文献：
  名称：

  Functional self-assembly of hydrogen-bonded 3D coordination networks constructed from 1,2,4,5-benzenetetracarboxylic acid

  摘要：

  Hydrothermal synthesis, characterization (IR, TG/DTA, element analysis, inductively coupled plasma (ICP)) and single-crystal X-ray structures of H(4)Btec hydrate and its two cobalt complexes, colorless [H(4)Btec center dot 2H(2)O] (n) (I), pink [Co(H2O)(6)(H(2)Btec)] (n) (II), and nacarat {[Co(H2O)(3)(H(2)Btec)(Phen)] center dot H2O} (n) (III) (H(4)Btec = 1,2,4,5-benzenetetracarboxylic acid, Phen = 1,10-phenanthroline) have been solved. The results showed that I forms a 3D O-H center dot center dot center dot O hydrogen-bonded network generated from H(4)Btec and water molecules, II presents a 3D network constructed by mononuclear [Co(H2O)(6)](2+) cations and H(2)Btec(2-) dianions through extensive hydrogen-bonding interactions, and III gives rise to a pseudo-octahedral coordination geometry. Extensive hydrogen-bonding interactions have significant effects in configuring a 3D network constructed by mononuclear [Co(H(2)Btec)(Phen)(H2O)(3)] neutral molecules and a water molecules.

  DOI：

  10.1134/s1070328407070019

文献信息

• Imaging compounds, methods of making imaging compounds, methods of imaging, therapeutic compounds, methods of making therapeutic compounds, and methods of therapy
  申请人：Chen Xiaoyuan

  公开号：US20080267882A1

  公开（公告）日：2008-10-30

  Embodiments of the present disclosure provide for RGD compounds that include a multimeric RGD (arginine-glycine-aspartic acid (Arg-Gly-Asp)) peptide, methods of making the RGD compound, pharmaceutical compositions including RGD compound, methods of using the RGD compositions or the pharmaceutical compositions including RGD compositions, methods of diagnosing and/or targeting angiogenesis related disease and related biological events, kits for diagnosing and/or targeting angiogenesis related disease and related biological events, and the like. In addition, the present disclosure includes compositions used in and methods relating to non-invasive imaging (e.g., positron emission tomography (PET) imaging) of the RGD compounds in vivo.

  本公开的实施例提供了包括多聚体RGD（精氨酸-甘氨酸-天冬氨酸（Arg-Gly-Asp））肽的RGD化合物，制备RGD化合物的方法，包括RGD化合物的药物组合物，使用RGD组合物或包括RGD组合物的药物组合物的方法，诊断和/或靶向血管生成相关疾病和相关生物事件的方法，用于诊断和/或靶向血管生成相关疾病和相关生物事件的试剂盒等。此外，本公开还包括用于体内非侵入性成像（例如正电子发射断层扫描（PET）成像）的RGD化合物的成分和方法。
• Compositions and Methods for Fermentation of Biomass
  申请人：Parekh Sarad

  公开号：US20100268000A1

  公开（公告）日：2010-10-21

  In one aspect, this invention relates to production of useful fermentation end-products from biomass through simultaneous hydrolysis and fermentation by a microorganism, such as Clostridium phytofermentans . The invention also relates to the development of a process for efficient pretreatment and conversion of lignocellulosic biomass to end-products with high conversion efficiency (yield). In another aspect, methods for producing a fermentation end-product by fermenting hexose (C6) and pentose (C5) sugars with a microorganism, such as Clostridium phytofermentans are disclosed herein.

  在一个方面，这项发明涉及通过微生物（如植物发酵槽菌）的同时水解和发酵，从生物质中生产有用的发酵终产物。该发明还涉及开发一种高效预处理和转化木质纤维素生物质为高转化效率（产率）的终产物的过程。在另一个方面，本文介绍了利用微生物（如植物发酵槽菌）发酵己糖（C6）和戊糖（C5）糖产生发酵终产物的方法。
• Use of multimodality nanostructures to detect target substances
  申请人：Emory University

  公开号：EP2325642A1

  公开（公告）日：2011-05-25

  Briefly described, embodiments of this disclosure include multimodality nanostructures, methods of forming the multimodality nanostructures, and methods of using the multimodality nanostructures.

  简而言之，本公开的实施方案包括多模态纳米结构、形成多模态纳米结构的方法以及使用多模态纳米结构的方法。
• Multimodality nanostructures, methods of fabrication thereof, and methods of use thereof
  申请人：Nie Shuming

  公开号：US20050265922A1

  公开（公告）日：2005-12-01

  Briefly described, embodiments of this disclosure include multimodality nanostructures, methods of forming the multimodality nanostructures, and methods of using the multimodality nanostructures.

  简而言之，本公开的实施方案包括多模态纳米结构、形成多模态纳米结构的方法以及使用多模态纳米结构的方法。
• MULTIMODALITY NANOSTRUCTURES, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF
  申请人：EMORY UNIVERSITY

  公开号：EP1743174A2

  公开（公告）日：2007-01-17