| 1064214-88-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• CAS: 1064214-88-5
• 化学式: C₃₂H₃₇F₃O₈
• 分子量: 606.636
• InChiKey: BLRJAELTMHUQDA-MNBDETKWSA-N

反应信息

• 作为产物：
  描述：

  13-hydroxylobolide 、 甲氧基-三氟甲基苯 在 吡啶 作用下， 以0.4 mg的产率得到
  参考文献：
  名称：

  Durumolides A–E, anti-inflammatory and antibacterial cembranolides from the soft coral Lobophytum durum

  摘要：

  Chemical investigations on the acetone extract of the soft coral Lobophytum durum have afforded five new cembranoids with a trans-fused alpha-methylene-gamma-lactone, durumolides A-E (1, 6, and 8-10), and five previously characterized cembrane-based diterpenoids (2-5 and 7). The Structures of the isolated metabolites were elucidated through extensive spectroscopic analyses, while the relative stereochemistry of 4 was confirmed by X-ray diffraction analyses. Moreover, the absolute configurations of 3-5 and 8 were established by application of modified Mosher's method. The anti-inflammatory effects, antibacterial activities, and inhibition assay of HCMV (Human cytomegalovirus) endonuclease activity of these isolated metabolites 1-10 were evaluated in Vitro. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.07.104