(1,2,5-Trimethyl-pyrrolidin-3-yl)-methanol | 90227-02-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: (1,2,5-Trimethyl-pyrrolidin-3-yl)-methanol
• 英文别名: (1,2,5-Trimethylpyrrolidin-3-yl)methanol
• CAS: 90227-02-4
• 化学式: C₈H₁₇NO
• 分子量: 143.229
• InChiKey: MLIOQXGHODUSCS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• ANTIVIRAL COMPOUNDS
  申请人：Gilead Sciences, Inc.

  公开号：US20150361087A1

  公开（公告）日：2015-12-17

  The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

  该披露涉及抗病毒化合物，含有这种化合物的组合物，包括给予这种化合物的治疗方法，以及用于制备这种化合物的有用过程和中间体。
• Platinum Compounds Of Malonic Acid Derivative Having Leaving Group Containing Amino Or Alkylamino
  申请人：BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD

  公开号：US20150368281A1

  公开（公告）日：2015-12-24

  Disclosed are a class of platinum compounds of malonic acid derivatives having a leaving group containing an amino or alkylamino, and pharmaceutically acceptable salt thereof, preparation method thereof and pharmaceutical composition containing the compounds. Also disclosed are uses of the compounds for treating cell proliferative diseases especially cancers. The platinum compounds of the present invention have high solubility in water, low toxicity and strong anti-tumor effect.
• US9725477B2
  申请人：——

  公开号：US9725477B2

  公开（公告）日：2017-08-08