2-Methyl-4-(methylthio)butan-2-amine | 1600814-98-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2-Methyl-4-(methylthio)butan-2-amine
• 英文别名: 2-methyl-4-methylsulfanylbutan-2-amine
• CAS: 1600814-98-9
• 化学式: C₆H₁₅NS
• 分子量: 133.26
• InChiKey: YFVBCAVONOZEII-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  51.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• N-SUBSTITUIERTE 8-[(2,6-DIFLUOROBENZYL)OXY]-2,6-DIMETHYLIMIDAZO[1,2-A]PYRAZIN-3-CARBOXAMID-DERIVATE ALS STIMULATOREN DER LÖSLICHEN GUANYLATCYCLASE (SGC) ZUR BEHANDLUNG VON KARDIOVASKULÄREN ERKRANKUNGEN
  申请人：Bayer Pharma Aktiengesellschaft

  公开号：EP3253758B1

  公开（公告）日：2019-04-03
• CHIRAL DESIGN
  申请人：WAVE LIFE SCIENCES LTD.

  公开号：US20210115444A1

  公开（公告）日：2021-04-22

  The present invention relates to chirally controlled oligonucleotides of select designs, chirally controlled oligonucleotide compositions, and methods of making and using the same. In some embodiments, a provided chirally controlled oligonucleotide composition provides different cleavage patterns of a nucleic acid polymer than a reference oligonucleotide composition. In some embodiments, a provided chirally controlled oligonucleotide composition provides single site cleavage within a complementary sequence of a nucleic acid polymer.