3-(4-(4-chlorophenoxy)phenyl)-2-(3-fluoro-5-methylphenyl)thiazolidin-4-one | 1059198-47-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(4-(4-chlorophenoxy)phenyl)-2-(3-fluoro-5-methylphenyl)thiazolidin-4-one
• 英文别名: 3-[4-(4-Chlorophenoxy)phenyl]-2-(3-fluoro-5-methylphenyl)-1,3-thiazolidin-4-one
• CAS: 1059198-47-8
• 化学式: C₂₂H₁₇ClFNO₂S
• 分子量: 413.9
• InChiKey: KZVSGNDZYZEHJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  54.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS
  申请人：Daily William

  公开号：US20080248511A1

  公开（公告）日：2008-10-09

  The present invention relates to single and dual reporter luminescence assays utilizing reagents to quench an optical, e.g., an enzyme-mediated luminescence, reaction. In one embodiment of the invention, a reagent is added to an assay which selectively quenches a first enzyme-mediated luminescence reaction without affecting a subsequent distinct enzyme-mediated luminescent reaction(s). An assay kit containing one or more selective quench reagents, and compositions comprising the quench reagent(s), are also provided.

  本发明涉及使用试剂熄灭光学反应（例如酶介导的发光反应）的单一和双重报告发光测定法。在本发明的一个实施例中，向测定中添加试剂，该试剂有选择地熄灭第一种酶介导的发光反应，而不影响随后的不同酶介导的发光反应。还提供了包含一种或多种选择性熄灭试剂的测定试剂盒，以及包含熄灭试剂的组合物。
• Compositions and methods to quench light from optical reactions
  申请人：——

  公开号：US20040224377A1

  公开（公告）日：2004-11-11

  The present invention relates to single and dual reporter luminescence assays utilizing reagents to quench an optical, e.g., an enzyme-mediated luminescence, reaction. In one embodiment of the invention, a reagent is added to an assay which selectively quenches a first enzyme-mediated luminescence reaction without affecting a subsequent distinct enzyme-mediated luminescent reaction(s). An assay kit containing one or more selective quench reagents, and compositions comprising the quench reagent(s), are also provided.

  本发明涉及利用试剂淬灭光学反应（如酶介导的发光反应）的单报告物和双报告物发光测定法。在本发明的一个实施方案中，将一种试剂添加到测定中，该试剂可选择性地淬灭第一个酶介导的发光反应，而不影响随后的不同酶介导的发光反应。本发明还提供了含有一种或多种选择性淬灭试剂的检测试剂盒，以及含有淬灭试剂的组合物。
• METHODS AND KITS FOR DUAL ENZYMATIC ASSAYS WHEREBY LIGHT IS QUENCHED FROM LUMINESCENT REACTIONS
  申请人：PROMEGA CORPORATION

  公开号：EP1592805A1

  公开（公告）日：2005-11-09
• [EN] METHODS AND KITS FOR DUAL ENZYMATIC ASSAYS WHEREBY LIGHT IS QUENCHED FROM LUMINESCENT REACTIONS<br/>[FR] PROCEDES ET KITS DE DOSAGES ENZYMATIQUES DOUBLES PERMETTANT DE DESACTIVER LA LUMIERE DE REACTIONS LUMINESCENTES
  申请人：PROMEGA CORP

  公开号：WO2004072299A1

  公开（公告）日：2004-08-26

  The present invention relates to single and dual reporter luminescence assays utilizing reagents to quench an optical, e.g., an enzyme-mediated luminescence, reaction. In one embodiment of the invention, a reagent is added to an assay which selectively quenches a first enzyme-mediated luminescence reaction without affecting a subsequent distinct enzyme-mediated luminescent reaction(s). An assay kit containing one or more selective quench reagents, and compositions comprising the quench reagent(s), are also provided.
• [EN] METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS<br/>[FR] PROCÉDÉS POUR RÉPRIMER DES RÉACTIONS OPTIQUES D'UNE LUMIÈRE
  申请人：PROMEGA CORP

  公开号：WO2008118445A1

  公开（公告）日：2008-10-02

  [EN] The present invention relates to single and dual reporter luminescence assays utilizing reagents to quench an optical, e.g., an enzyme-mediated luminescence, reaction. In one embodiment of the invention, a reagent is added to an assay which selectively quenches a first enzyme-mediated luminescence reaction without affecting a subsequent distinct enzyme-mediated luminescent reaction(s). An assay kit containing one or more selective quench reagents, and compositions comprising the quench reagent(s), are also provided.
  [FR] La présente invention concerne des essais de luminescence de rapport unique ou double utilisant des agents réactifs afin de réprimer une réaction optique, par exemple, une luminescence obtenue par enzyme. Dans un mode de réalisation de la présente invention, un agent réactif est ajouté à un essai qui réprime sélectivement une première réaction de luminescence obtenue par enzyme sans influencer une ou des réactions luminescentes obtenues par enzyme distinctes subséquentes. Un kit d'essai contenant un ou plusieurs agents réactifs de répression sélective et des compositions comprenant le ou les agents réactifs de répression sont également fournis.