1-Chlor-2,3-dimethyl-5-nitro-benzol | 67405-07-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Chlor-2,3-dimethyl-5-nitro-benzol
• 英文别名: 1-chloro-2,3-dimethyl-5-nitro-benzene；1-Chloro-2,3-dimethyl-5-nitrobenzene
• CAS: 67405-07-6
• 化学式: C₈H₈ClNO₂
• 分子量: 185.61
• InChiKey: MVCOZQHAVNWKGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• CYCLOALKYL CONTAINING ANILIDE LIGANDS FOR THE THYROID RECEPTOR
  申请人：Bristol-Myers Squibb Company

  公开号：EP1587783A2

  公开（公告）日：2005-10-26
• EP1587783A4
  申请人：——

  公开号：EP1587783A4

  公开（公告）日：2006-11-08
• [EN] CYCLOALKYL CONTAINING ANILIDE LIGANDS FOR THE THYROID RECEPTOR<br/>[FR] CYCLOALKYLE CONTENANT DES LIGANDS ANILIDE POUR LE RECEPTEUR DES HORMONES THYROIDIENNES
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2004066929A2

  公开（公告）日：2004-08-12

  Novel thyroid receptor ligands are provided having the general Formula (I) wherein X, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11, are as defined herein. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolic dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described above is administered in a therapeutically effective amount.