5-((5-(isopropoxymethyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-(phenylimino)thiazolidin-4-one | 1338212-56-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-((5-(isopropoxymethyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-(phenylimino)thiazolidin-4-one
• CAS: 1338212-56-8
• 化学式: C₁₈H₂₂N₂O₄S
• 分子量: 362.45
• InChiKey: IEQPSBRCQMGQLO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.84
• 重原子数：
  25.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  76.99
• 氢给体数：
  1.0
• 氢受体数：
  6.0

文献信息

• Synthesis of 2-substituted aminothiazol-4(5H)-ones proceeding from carboxylactones
  作者：T. V. Kochikyan、M. A. Samvelyan、V. S. Arutyunyan

  DOI：10.1134/s1070428011080148

  日期：2011.8

  New representatives of 2,2,4-trisubstituted butano-4-lactones were synthesized. By a series of transformations the corresponding gamma-carboxylactones were obtained. The latter served as starting compounds for preparation of heteryl-linked lactones, 5-[5-(alkoxymethyl)-2-oxotetrahydrofuran-3-yl}methyl]-2-arylaminothiazol-4(5H)-ones.