3-ethyl-4-hydroxy-2H-furan-5-one | 136400-56-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 英文名称: 3-ethyl-4-hydroxy-2H-furan-5-one
• CAS: 136400-56-1
• 化学式: C₆H₈O₃
• 分子量: 128.128
• InChiKey: XGLAYVYTRTVSAY-UHFFFAOYSA-N

物化性质

• 沸点：
  327.9±42.0 °C(Predicted)
• 密度：
  1.280±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  α-Keto-β-ethyl-β-allyloxycarbonyl-γ-butyrolactone 在 tris(dibenzylideneacetone)dipalladium(0) chloroform complex 、 三苯基膦 甲酸铵 作用下， 以 四氢呋喃 为溶剂， 以86%的产率得到3-ethyl-4-hydroxy-2H-furan-5-one
  参考文献：
  名称：

  α-羟基丁烯内酯和α-酮-β-烯丙基-γ-丁内酯的简便合成

  摘要：

  在钯催化剂存在下，α-酮基-β-烷基-β-烯丙氧基羰基-γ-丁内酯与甲酸铵反应以良好的收率得到α-羟基丁烯内酯。当反应在没有甲酸铵的情况下进行时，发生脱羧-烯丙基化，得到 α-羟基丁烯内酯的烯丙醇醚，通过热克莱森重排将其转化为 α-酮基-β-烯丙基-γ-丁内酯。

  DOI：

  10.1246/cl.1991.1349

文献信息

• [EN] FRAGRANCE COMPOSITIONS COMPRISING COMPOUNDS WITH OLFACTORY QUALITIES<br/>[FR] COMPOSITIONS PARFUMÉES COMPRENANT DES COMPOSANTS AYANT DES QUALITÉS OLFACTIVES
  申请人：P2 SCIENCE INC

  公开号：WO2017139637A1

  公开（公告）日：2017-08-17

  The application relates to compositions comprising compounds of Formula I, Formula II, or Formula III and the use of these compositions in the fragrance industry, i.e., for the production of perfumes, air fresheners, laundry detergents, household cleaning products, liquid or bar soaps, shampoos, conditioners, hair sprays, cosmetics, deodorants, insect repellants, insecticides, and pet litter.

  该申请涉及包含式I、式II或式III化合物的组合物，以及这些组合物在香精行业中的应用，即用于生产香水、空气清新剂、洗衣液、家庭清洁产品、液体或固体肥皂、洗发水、护发素、发胶、化妆品、除臭剂、驱虫剂、杀虫剂和宠物猫砂。
• FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEOPENTYL GLYCOL DIACETATE
  申请人：P2 Science, Inc.

  公开号：EP3247691A1

  公开（公告）日：2017-11-29
• OLFACTIVE COMPOSITIONS COMPRISING CYCLOHEXYL-ALKYL CARBINOLS
  申请人：P2 Science, Inc.

  公开号：EP3303534A1

  公开（公告）日：2018-04-11
• FRAGRANCE COMPOSITIONS COMPRISING COMPOUNDS WITH OLFACTORY QUALITIES
  申请人：P2 Science, Inc.

  公开号：EP3414309A1

  公开（公告）日：2018-12-19
• AQUEOUS LIQUID FRAGRANCE COMPOSITION AND AQUEOUS LIQUID FRAGRANCE USING SAME
  申请人：Hatakeyama Tadahide

  公开号：US20140162932A1

  公开（公告）日：2014-06-12

  The present invention provides an aqueous liquid fragrance composition which contains a fragrance, gluconate, an anionic surfactant, a non-ionic surfactant and water, the sum of the amounts of the anionic surfactant and the non-ionic surfactant contained per 1 part by weight of the fragrance being 0.3 to 1.4 parts by weight, and also provides an aqueous liquid fragrance using the same. By containing gluconate, an anionic surfactant and a non-ionic surfactant in an aqueous liquid fragrance composition, this composition of the present invention makes it possible to reduce the amount of a surfactant for solubilizing the fragrance in water. In the present invention, reducing the amount of a surfactant for solubilizing the fragrance in water makes it possible to provide an aqueous liquid fragrance composition and aqueous liquid fragrance using the same whereby favorable volatility can be upheld during use, transparency can be maintained, and the appearance will not be adversely affected.