1-(2,6-dimethoxy-pyrimidin-4-yl)-3-(toluene-4-sulfonyl)-urea | 92296-92-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2,6-dimethoxy-pyrimidin-4-yl)-3-(toluene-4-sulfonyl)-urea
• 英文别名: 1-(2,6-Dimethoxypyrimidin-4-yl)-3-(4-methylphenyl)sulfonylurea
• CAS: 92296-92-9
• 化学式: C₁₄H₁₆N₄O₅S
• 分子量: 352.371
• InChiKey: AKDLOHWMYMAHFF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  128
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Herbicidal sulphonamides, their preparation, compositions containing them and use thereof
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0001485A2

  公开（公告）日：1979-04-18

  Herbicidal N - (heterocyclicaminocarbonyl)- sulfonamides, and preparation and use thereof, having the general formula wherein R is an aromatic organic group, W is oxygen or sulphur and X and Y are hydrogen, chlorine, bromine, methyl, methoxy or ethoxy. The compounds may be made by reacting 4-aminopyrimidine with an isocyanate or isothiocyanate. They can be formulated for agricultural use with a surface active agent and/or a solid or liquid diluent, and can be used pre- or post-emergence for controlling weeds or for regulating plant growth.

  除草剂 N-（杂环氨基羰基）-磺酰胺及其制备方法和用途，其通式中 R 为芳香族有机基团，W 为氧或硫，X 和 Y 为氢、氯、溴、甲基、甲氧基或乙氧基。 这些化合物可通过 4-氨基嘧啶与异氰酸酯或异硫氰酸酯反应制得。 它们可与表面活性剂和/或固体或液体稀释剂配制成农用配方，并可在萌芽前或萌芽后用于控制杂草或调节植物生长。
• Herbicidal sulfamates and preparation and use thereof
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0004163A1

  公开（公告）日：1979-09-19

  N-(Heterocyclicaminocarbonyl) arylsulfamates of the general formula wherein R1 is H, OCH3 or alkyl of 1-3 carbons; X and Y are CH3, CH3CH2, various alkoxy groups, CH3S, CH3CH2S, or X may be CF3 or Cl; Z is CH or N; R2-R6 are H or various substituents; and agriculturally suitable salts thereof, are of interest for plant growth retardation, brush control and weed control in crops. They may be made by reacting an appropriate arylox- aryloxysulfonyl isocyanate with an appropriate 2-aminopyrimidine or 2-amino-1,3,5-triazine. For use, an effective amount of the compound is applied to the locus of the undesired vegetation to be controlled.

  通式为 N-(杂环氨基羰基)芳基氨基磺酸盐 其中 R1 为 H、O 或 1-3 个碳原子的烷基； X 和 Y 是 CH3、 CH2、各种烷氧基、 S、 CH2S，或 X 可以是 CF3 或 Cl； Z 是 CH 或 N； R2-R6 是 H 或各种取代基； 及其农业上适用的盐类，可用于作物的植物生长延缓、灌木丛控制和杂草控制。它们可通过适当的芳氧基-芳氧基磺酰基异氰酸酯与适当的 2-氨基嘧啶或 2-氨基-1,3,5-三嗪反应制成。使用时，将有效量的化合物施用到需要控制的不想要的植被上。
• Herbicidal pyridinesulfonamides, preparation and use thereof and compositions containing them
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0013480A2

  公开（公告）日：1980-07-23

  Pyridinesulfonamides of a general formula and their agriculturally suitable salts wherein: R1 and R2 are H or various substituents; R3 and R. are independently H or CH3; W is O or S: and R is a pyrimidyl or triazinyl residue which may be substituted; are of interest as herbicides for preemergence or post- emergence application and for regulating plant growth. The compounds can be made e.g. by reacting an appropriate pyridylsulfonyl isocyanate or isothiocyanate with an appropriate amino- or methylamino-substituted pyrimidine or triazine. The compounds can be formulated for use in conventional manner.

  通式为吡啶磺酰胺及其农业上适用的盐类，其中：R1 和 R2 为 H 或各种取代基；R3 和 R 独立地为 H 或 CH3；W 为 O 或 S；R 为可被取代的嘧啶基或三嗪基残基。 这些化合物可用作除草剂，用于萌芽前或萌芽后施药以及调节植物生长。 例如，可通过将适当的吡啶磺酰基异氰酸酯或异硫氰酸酯与适当的氨基或甲氨基取代的嘧啶或三嗪反应来制造这些化合物。 这些化合物可按常规方式配制使用。
• Herbicidal thiophenesulfonamides, and preparation, compositions and use thereof
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0017473A1

  公开（公告）日：1980-10-15

  Compounds of the formula: wherein R is C,-C4 alkyl, N02, Cl, Br, SO2NR1R2 where R, and R2 are selected from C1-C3 alkyl; X is H, Cl, Br, CH3, CH3CH2, alkoxy C,-C3, CF3, CH3S or CH30CH2; Y is CH3 or CH30; and Z is CH or N; and agriculturally suitable salts thereof, exhibit herbicidal activity especially against broadleaf weeds; they are selective in certain crops, e.g. wheat and barley. The compounds can be formulated for use in conventional manner. They may be made by reacting an appropriately substituted 2-aminotriazine or 2-aminopyrimidine with a substituted thiophenenesulfonyl isocyanate.

  式中的化合物： 式中 R是C,-C4烷基、N02、Cl、Br、SO2NR1R2，其中R和R2选自C1-C3烷基； X 是 H、Cl、Br、CH3、 CH2、C,-C3 烷氧基、CF3、 S 或 0CH2； Y 是 或 0；以及 Z 是 CH 或 N； 及其农业上适用的盐类具有除草活性，特别是对阔叶杂草；它们对某些作物，如小麦和大麦具有选择性。这些化合物可按常规方法配制使用。它们可以通过适当取代的 2-氨基三嗪或 2-氨基嘧啶与取代的噻吩磺酰基异氰酸酯反应制成。
• Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0023141A2

  公开（公告）日：1981-01-28

  Compounds of the formulae and wherein: A is selected from certain substituted amino, haloalkoxy or aryloxy groups; R1 is hydrogen, halogen, nitro or various organic groups; R'1 is H, Cl, F, Br, CH3 or OCH3; R, and R5 are independently H or CH3 but not both CH,; R6 is a pyrimidyl or triazinyl residue which may be substituted; W is oxygen or sulfur; Z is CH or N; X, and Y, are H, CH3 or various alkoxy groups, but cannot both be H; and B is selected from various aliphatic or aromatic organic groups; and their agriculturally suitable salts, exhibit potent herbicidal activity. Some may also exhibit plant growth regulant activity. The compounds (I) and (IA) can be formulated for use in conventional manner. The compounds (I) can be made inter alia by reacting an isocyanate or isothiocyanate of general formula with an amine HNR Rm. The compounds (I) can be converted into compounds (IA) by reacting an alkali metal or alkaline earth metal salt thereof with an appropriate halide BI or BBr. The novel intermediates (IB) also form part of the invention. They can be made from the corresponding sulfonamide by various phosgenation reactions.

  式中的化合物 和 其中 A 选自某些取代的氨基、卤代烷氧基或芳氧基基团； R1 是氢、卤素、硝基或各种有机基团 R'1 是 H、Cl、F、Br、CH3 或 O ； R,和 R5 独立地为 H 或 ，但不能同时为 CH,； R6 是可被取代的嘧啶或三嗪残基； W 是氧或硫 Z 是 CH 或 N； X 和 Y 是 H、 或各种烷氧基，但不能都是 H；以及 B 选自各种脂肪族或芳香族有机基团； 以及它们在农业上适用的盐类，具有强大的除草活性。有些化合物还具有植物生长调节活性。化合物（I）和（IA）可按常规方法配制使用。 化合物 (I) 的制备方法包括将通式为 与胺 HNR Rm 反应制得。化合物（I）可通过其碱金属盐或碱土金属盐与适当的卤化物 BI 或 BBr 反应转化为化合物（IA）。 新型中间体（IB）也是本发明的一部分。它们可以由相应的磺酰胺通过各种磷化反应制得。