cyclobis(1,4-phenylene-4,4'-diyl diethylphosphoramidite) | 370098-13-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: cyclobis(1,4-phenylene-4,4'-diyl diethylphosphoramidite)
• 英文别名: cyclobis(1,4-phenylene diethylphosphoramidite)；3-N,3-N,10-N,10-N-tetraethyl-2,4,9,11-tetraoxa-3,10-diphosphatricyclo[10.2.2.25,8]octadeca-1(15),5,7,12(16),13,17-hexaene-3,10-diamine
• CAS: 370098-13-8
• 化学式: C₂₀H₂₈N₂O₄P₂
• 分子量: 422.401
• InChiKey: LXMBMEDRVIOHGA-UHFFFAOYSA-N

物化性质

• 沸点：
  467.6±55.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.05
• 重原子数：
  28.0
• 可旋转键数：
  6.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  43.4
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  cyclobis(1,4-phenylene-4,4'-diyl diethylphosphoramidite) 在 双氧水 、 尿素 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以91%的产率得到cyclobis(1,4-phenylene diethylphosphoramidate)
  参考文献：
  名称：

  摘要：

  The first representatives of linear phosphocyclophanes were prepared starting from hydroquinone or 4,4'-dihydroxybiphenyl and phosphorous triamides. The reaction course is influenced by the structures of the aromatic diol and alkyl substituents in the phosphamide moiety. The phosphorus atom readily enters redox reactions and complexation. The complexing power of the aromatic fragments of the synthesized molecules is lower than that of classical p-cyclophanes.

  DOI：

  10.1023/a:1012357001662
• 作为产物：
  描述：

  对苯二酚 以 乙腈 为溶剂， 反应 28.0h， 生成 cyclobis(1,4-phenylene-4,4'-diyl diethylphosphoramidite)
  参考文献：
  名称：

  摘要：

  The first representatives of linear phosphocyclophanes were prepared starting from hydroquinone or 4,4'-dihydroxybiphenyl and phosphorous triamides. The reaction course is influenced by the structures of the aromatic diol and alkyl substituents in the phosphamide moiety. The phosphorus atom readily enters redox reactions and complexation. The complexing power of the aromatic fragments of the synthesized molecules is lower than that of classical p-cyclophanes.

  DOI：

  10.1023/a:1012357001662

文献信息

• Dismutation of arylene phosphorodiamidites: Specific features and aspects of preparative use
  作者：E. N. Rasadkina、P. V. Slitikov、E. E. Nifant’ev

  DOI：10.1134/s1070363206020046

  日期：2006.2

  The dismutation ofarylene phosphorodiamidites derived from the simplest phenols and naphthols and of their dibasic analogs was studied. The main regular trends of this process and the limits of its synthetic applicability were determined.
• Dismutation of Bisphosphorylated Aromatic Diols
  作者：Edward E. Nifantyev、Elena N. Rasadkina、Pavel V. Slitikov、Larisa K. Vasyanina

  DOI：10.1080/104265090517244

  日期：2005.2

  The first study of the dismutation of aromatic diol bisdiantidophosphites has been performed. Derivatives of condensed aromatic systems dismutate more rapidly than their mononuclear analogues. Amide derivatives with aliphatic substituents at the nitrogen atom undergo dismutation more readily than their heterocyclic analogues. In methylene chloride, the process proceeded most rapidly regardless of the aromatic component and the substititent at the phosphorus atom. Apolar solvents (benzene and diethyl ether) did not favor the dismutation. Temperature had no effect oil the time of dismutation, and a catalyst decreased it by a factor of 1.5-2.