diethyl-propyl-phosphine | 55942-99-9

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: diethyl-propyl-phosphine
• 英文别名: Diaethyl-propyl-phosphin；Diethyl(propyl)phosphane
• CAS: 55942-99-9
• 化学式: C₇H₁₇P
• 分子量: 132.186
• InChiKey: SHCATAMMUJGPTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 diethyl-propyl-phosphine
  参考文献：
  名称：

  Collie, Journal of the Chemical Society, 1888, vol. 53, p. 723

  摘要：

  DOI：

文献信息

• ANTIMICROBIAL CATIONIC POLYCARBONATES
  申请人：INTERNATIONAL BUSINESS MACHINES CORPORATION

  公开号：US20140301967A1

  公开（公告）日：2014-10-09

  Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.

  具有一个或两个阳离子聚碳酸酯链的抗菌阳离子聚合物是通过有机催化的环氧开聚合制备的。其中一种抗菌阳离子聚合物具有基本由阳离子碳酸酯重复单元构成的聚合物链，与一个或两个末端基团相连。末端基团可以包括胆固醇等生物活性化合物的共价结合形式。其他抗菌阳离子聚合物具有随机共聚碳酸酯链，其中含有少量疏水重复单元，带有维生素E和/或维生素D2的共价结合形式。这些阳离子聚合物对革兰氏阴性和革兰氏阳性微生物和真菌表现出高活性和选择性。
• Method for preparing aminoarylborane compounds or derivatives thereof
  申请人：Université de Bordeaux I

  公开号：EP2881398A1

  公开（公告）日：2015-06-10

  The present invention provides a process for the preparation of aminoarylborane compounds and derivatives thereof comprising a step of arylation by reacting an aryl chloride with an aminoborane compound in the presence of a catalytic system. Typically, the transformation comprises, converting Aryl-chloride Ar-Cl with an aminoborane such as into an aminoarylborane compound of the following formula:

  本发明提供了一种制备氨基芳基硼化合物及其衍生物的方法，包括通过在催化体系存在下，将芳基氯化物与氨基硼烷化合物反应进行芳基化的步骤。通常，该转化包括将芳基氯化物Ar-Cl与氨基硼烷化合物反应，转化为以下式的氨基芳基硼化合物：
• [EN] HOMOGENOUS PROCESS FOR THE HYDROGENATION OF CARBOXYLIC ACIDS AND DERIVATIVES THEREOF<br/>[FR] PROCEDE HOMOGENE D'HYDROGENATION D'ACIDES CARBOXYLIQUES ET DE DERIVES DE CEUX-CI
  申请人：DAVY PROCESS TECHN LTD

  公开号：WO2003093208A1

  公开（公告）日：2003-11-13

  A homogenous process for the hydrogenation of the carboxylic acids and/or derivatives thereof in the presence of a catalyst comprising ruthenium, rhodium, iron, osmium or palladium, and an organic phosphine is described in which the hydrogenation is carried out in the presence of at least about 1% by weight water. A process for regenerating a catalyst comprising ruthenium, rhodium, iron, osmium or palladium and an organic phosphine is also described in which the regeneration is carried out in the presence of hydrogen and water.

  在存在包含钌、铑、铁、锇或钯的催化剂以及有机膦的情况下，描述了一种用于羧酸及/或其衍生物的加氢反应的均相过程，其中加氢反应在至少约1%重量的水存在下进行。还描述了一种用于再生包含钌、铑、铁、锇或钯和有机膦的催化剂的过程，其中再生在氢气和水的存在下进行。
• METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS
  申请人：MARUZEN PETROCHEMICAL CO., LTD.

  公开号：US20160108071A1

  公开（公告）日：2016-04-21

  The present invention provides a method for easily and inexpensively producing a heterogeneous catalyst used to synthesize a cyclic carbonate by reacting an epoxide with carbon dioxide and having excellent catalyst activity; a catalyst obtained using said manufacturing method; and a method for synthesizing a cyclic carbonate using said catalyst. A method for producing a catalyst that is used for the purpose of synthesizing a cyclic carbonate by subjecting to a reaction an epoxide with carbon dioxide, said method comprising the following steps (a) and (b): (a) a step of obtaining a catalyst precursor having a haloalkyl group or a haloaryl group by reacting a silane compound with a silica gel in the presence of xylene, the silane compound having a haloalkyl group or a haloaryl group and (b) a step of obtaining a catalyst for synthesizing a cyclic carbonate by reacting the catalyst precursor obtained in step (a) with a tertiary phosphine.

  本发明提供了一种用于通过将环氧化合物与二氧化碳反应来合成环状碳酸酯的异质催化剂的简便且廉价的生产方法；采用所述制备方法获得的催化剂；以及使用该催化剂合成环状碳酸酯的方法。用于生产一种用于合成环状碳酸酯的催化剂的方法，通过将环氧化合物与二氧化碳反应，该方法包括以下步骤(a)和(b)：(a)通过在二甲苯存在下将硅烷化合物与二氧化硅反应以获得具有卤代烷基或卤代芳基的催化剂前驱体的步骤，其中所述硅烷化合物具有卤代烷基或卤代芳基；以及(b)通过将步骤(a)中获得的催化剂前驱体与三膦反应以获得用于合成环状碳酸酯的催化剂的步骤。
• VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS
  申请人：INTERNATIONAL BUSINESS MACHINES CORPORATION

  公开号：US20180117162A1

  公开（公告）日：2018-05-03

  Gel-forming block copolymers were prepared comprising i) a central hydrophilic block consisting essentially of a divalent poly(ethylene oxide) chain and ii) two peripheral monocarbonate or polycarbonate hydrophobic blocks linked to the central block by linking groups bearing one or more hydrogen bond forming *—N(H)—* groups. The hydrophobic blocks comprise one or more vitamin-bearing subunits. The gel-forming block copolymers can be used to prepare various biodegradable and/or biocompatible hydrogel and organogel drug compositions, in particular antimicrobial and/or anti-tumor drug compositions. The hydrogel compositions have utility in depot injections for drug delivery. The hydrogen bonding *—N(H)—* group(s) provide longer in vivo lifetime of the hydrogel before degradation and a more prolonged and controlled release rate of a hydrophobic drug compared to similar hydrogels prepared from poly(ethylene glycol).

  制备了包含以下组成部分的凝胶形成嵌段共聚物：i）主要由二价聚乙二醇链组成的中心亲水性块和ii）通过带有一个或多个氢键形成*—N(H)—*基团连接到中心块的两个外周单碳酸酯或多碳酸酯疏水性块。疏水性块包含一个或多个含维生素的亚单位。这些凝胶形成嵌段共聚物可用于制备各种可生物降解和/或生物相容的水凝胶和有机凝胶药物组合物，特别是抗微生物和/或抗肿瘤药物组合物。水凝胶组合物在药物输送的库存注射中具有实用性。与由聚乙二醇制备的类似水凝胶相比，氢键*—N(H)—*基团提供了凝胶在体内降解之前更长的生命周期，以及与水凝胶相比更延长和控制释放速率的疏水性药物。