(3-hydroxy-2,5-dioxo-pyrrolidin-3-yl)-acetic acid | 13345-87-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: (3-hydroxy-2,5-dioxo-pyrrolidin-3-yl)-acetic acid
• 英文别名: (3-Hydroxy-2,5-dioxo-pyrrolidin-3-yl)-essigsaeure；2-(3-Hydroxy-2,5-dioxopyrrolidin-3-yl)acetic acid
• CAS: 13345-87-4
• 化学式: C₆H₇NO₅
• 分子量: 173.125
• InChiKey: BMAOZZZDJCXRJS-UHFFFAOYSA-N

物化性质

• 沸点：
  555.6±35.0 °C(Predicted)
• 密度：
  1.643±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  citric acid α,α'-diethyl ester-β-amide 生成 (3-hydroxy-2,5-dioxo-pyrrolidin-3-yl)-acetic acid
  参考文献：
  名称：

  Schroeter, Chemische Berichte, 1905, vol. 38, p. 3199

  摘要：

  DOI：

文献信息

• POLYMER AND COMPOSITION
  申请人：DSM IP ASSETS B.V.

  公开号：US20160237213A1

  公开（公告）日：2016-08-18

  The present invention relates to a polyester resin obtained by reaction in a process (I) between the following components A to E to obtain a polyester P (the polyester comprising an alkyd resin and/or a saturated polyester resin), where (A) Component A (also referred to herein as the Imide and/or Imide Component) comprises one or more cyclic imides of Formula (1); where R′ represents a divalent optionally substituted saturated C 1-30 organo moiety; and R represents H or a monovalent optionally substituted saturated C 1-30 organo moiety; (A′) Optional Component A′ comprises saturated dicarboxylic acid and/or saturated hydroxyacid and that is not optional in case component A does not comprise a dicarboxylic acid or a hydroxyacid; 1(B) Component B (also referred to herein as the Polyol and/or Polyol Component) comprises at least one saturated polyhydric alcohol; (C) Optional Component C (also referred to herein as the Rosin and/or Rosin Component) comprises naturally occurring rosin, the rosin comprising from 40 to 80 parts per hundred by weight of rosin of an unsaturated mono carboxylic acid comprising at least one C 5-25 cyclohydrocarbo moiety capable of undergoing a Diels Alder or Ene reaction; (D) Optional Component D (also referred to herein as the Fatty Acid and/or Fatty Acid Component) comprises at least one linear C 2-60 hydrocarbo carboxylic acid optionally comprising at least two linoleically unsaturated double bonds; 2(E) Optional Component E (also referred to as the Other Component E) which may comprise at least one monofunctional or polyfunctional monomer other than any of Components A to D.

  本发明涉及通过在以下组分A到E之间的过程（I）中反应获得的聚酯树脂P（聚酯包括醇酸树脂和/或饱和聚酯树脂），其中（A）组分A（在此也称为咪唑和/或咪唑组分）包括公式（1）的一个或多个环状咪唑；其中R'表示二价的、可选取代的饱和的C1-30有机基团；R表示H或一价的、可选取代的饱和的C1-30有机基团；（A'）可选组分A'包括饱和的二羧酸和/或饱和的羟酸，在组分A不包括二羧酸或羟酸的情况下不是可选的；（B）组分B（在此也称为多元醇和/或多元醇组分）包括至少一种饱和的多元醇；（C）可选组分C（在此也称为松香和/或松香组分）包括天然存在的松香，该松香包括每百份重量的松香中40至80份的不饱和单羧酸，该不饱和单羧酸包括至少一个可进行Diels Alder或Ene反应的C5-25环烃基团；（D）可选组分D（在此也称为脂肪酸和/或脂肪酸组分）包括至少一种线性的C2-60碳氢基团羧酸，可选包括至少两个亚油酸不饱和双键；（E）可选组分E（也称为其他组分E）可能包括至少一种单官能团或多官能团单体，除了组分A到D中的任何一种。
• Polymer and composition
  申请人：DSM IP ASSETS B.V.

  公开号：US10167365B2

  公开（公告）日：2019-01-01

  The present invention relates to a polyester resin obtained by reaction in a process (I) between the following components A to E to obtain a polyester P (the polyester comprising an alkyd resin and/or a saturated polyester resin), where (A) Component A (also referred to herein as the Imide and/or Imide Component) comprises one or more cyclic imides of Formula (1); where R′ represents a divalent optionally substituted saturated C1-30 organo moiety; and R represents H or a monovalent optionally substituted saturated C1-30 organo moiety; (A′) Optional Component A′ comprises saturated dicarboxylic acid and/or saturated hydroxyacid and that is not optional in case component A does not comprise a dicarboxylic acid or a hydroxyacid; 1(B) Component B (also referred to herein as the Polyol and/or Polyol Component) comprises at least one saturated polyhydric alcohol; (C) Optional Component C (also referred to herein as the Rosin and/or Rosin Component) comprises naturally occurring rosin, the rosin comprising from 40 to 80 parts per hundred by weight of rosin of an unsaturated mono carboxylic acid comprising at least one C5-25 cyclohydrocarbo moiety capable of undergoing a Diels Alder or Ene reaction; (D) Optional Component D (also referred to herein as the Fatty Acid and/or Fatty Acid Component) comprises at least one linear C2-60 hydrocarbo carboxylic acid optionally comprising at least two linoleically unsaturated double bonds; 2(E) Optional Component E (also referred to as the Other Component E) which may comprise at least one monofunctional or polyfunctional monomer other than any of Components A to D.

  本发明涉及一种聚酯树脂，通过下列组分A至E在工艺(I)中反应得到聚酯P(该聚酯包括醇酸树脂和/或饱和聚酯树脂)，其中(A)组分A(在此也称为酰亚胺和/或酰亚胺组分)包括一个或多个式(1)的环状酰亚胺；其中R′代表二价任选取代的饱和C1-30有机分子；(A′) 可选组分 A′包括饱和二羧酸和/或饱和羟基酸，在组分 A 不包括二羧酸或羟基酸的情况下，这不是可选组分； 1(B) 组分 B（此处也称为多元醇和/或多元醇组分）包括至少一种饱和多元醇；(C) 可选组分 C(在此也称为松香和/或松香组分)包括天然松香，松香包括按 重量计 40 至 80 份的不饱和一元羧酸松香，该不饱和一元羧酸包含至少一 个能够发生 Diels Alder 或 Ene 反应的 C5-25 环氢羧基；(D) 可选组分 D（此处也称为脂肪酸和/或脂肪酸组分）包括至少一种线性 C2-60 碳氢羧酸，可选地包括至少两个亚油不饱和双键； 2 (E) 可选组分 E（此处也称为其他组分 E）可包括至少一种单官能团或多官能团单体， 但不包括组分 A 至 D 中的任何一种。
• Luminescent compositions and applications thereof
  申请人：THE PENN STATE RESEARCH FOUNDATION

  公开号：US10648917B2

  公开（公告）日：2020-05-12

  In one aspect, methods of sensing are described herein. In some embodiments, a method of sensing includes disposing a fluorophore in a biological environment, wherein the fluorophore includes a dioxo-pyridine ring (DPR) or a thiazolopyridine acid (TPA). The method further includes exposing the biological environment to electromagnetic radiation having a wavelength corresponding to an excitation wavelength of the fluorophore, detecting light emitted by the fluorophore, and correlating the light emitted by the fluorophore to a presence or absence of an analyte within the biological environment in an amount above a minimum detection threshold. The presence of the analyte can increase or decrease the amount of light emitted by the fluorophore. The presence of the analyte may also shift the peak emission wavelength or alter the fluorescence lifetime of the fluorophore. The analyte, in some embodiments, includes hydrogen ions, halide ions, and/or halogens.

  在一个方面，本文描述了传感方法。在一些实施例中，传感方法包括在生物环境中放置荧光团，其中荧光团包括二氧吡啶环（DPR）或噻唑吡啶酸（TPA）。该方法还包括将生物环境暴露于电磁辐射中，电磁辐射的波长与荧光团的激发波长相对应，检测荧光团发出的光，并将荧光团发出的光与生物环境中分析物的存在或不存在相关联，分析物的量超过最小检测阈值。分析物的存在可增加或减少荧光团发出的光量。被分析物的存在还可能移动峰值发射波长或改变荧光团的荧光寿命。在某些实施方案中，分析物包括氢离子、卤化物离子和/或卤素。
• PREPARATION OF PROTEIN/POLYSACCHARIDE CONJUGATE VACCINES USING HOMOBIFUNCTIONAL AND HETEROBIFUNCTIONAL VINYLSULFONES
  申请人：Virion Systems, Inc.

  公开号：EP0930895A1

  公开（公告）日：1999-07-28
• EP2430134B1
  申请人：——

  公开号：EP2430134B1

  公开（公告）日：2016-03-16