(6-chloro-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-(4-fluoro-phenyl)-amine | 1454654-12-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三唑并吡嗪类
• 英文名称: (6-chloro-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-(4-fluoro-phenyl)-amine
• 英文别名: 6-chloro-N-(4-fluorophenyl)-[1,2,4]triazolo[1,5-a]pyrazin-2-amine
• CAS: 1454654-12-6
• 化学式: C₁₁H₇ClFN₅
• 分子量: 263.661
• InChiKey: KQQIZGMEUQRIEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  55.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] TRIAZOLOPYRAZINE DERIVATIVES<br/>[FR] DÉRIVÉS DE TRIAZOLOPYRAZINE
  申请人：MERCK PATENT GMBH

  公开号：WO2013131609A1

  公开（公告）日：2013-09-12

  Compounds of the formula (I) in which R1, R2 and R4 have the meanings indicated in Claim 1, are inhibitors of GCN2, and can be employed, inter alia, for the treatment of cancer.

  式(I)中R1、R2和R4具有权利要求1中所指示的含义的化合物是GCN2的抑制剂，可用于治疗癌症。
• TRIAZOLOPYRAZINE DERIVATIVES
  申请人：Merck Patent GmbH

  公开号：US20150051202A1

  公开（公告）日：2015-02-19

  Compounds of the formula I in which R 1 , R 2 and R 4 have the meanings indicated in Claim 1, are inhibitors of GCN2, and can be employed, inter alia, for the treatment of cancer.

  公式I中，R1、R2和R4的含义如权利要求1所示的化合物是GCN2的抑制剂，可以用于治疗癌症等疾病。
• POLYELECTROLYTE COMPLEXES FOR BIOCIDE ENHANCEMENT
  申请人：Ceradis B.V.

  公开号：EP2836073A1

  公开（公告）日：2015-02-18
• POLYELECTROLYTE COMPLEXES COMPRISING NATAMYCINE AND/OR PHOSPHITE FOR BIOCIDE ENHANCEMENT
  申请人：Ceradis B.V.

  公开号：EP2838362A1

  公开（公告）日：2015-02-25
• [EN] POLYELECTROLYTE COMPLEXES FOR BIOCIDE ENHANCEMENT<br/>[FR] COMPLEXES POLYÉLECTROLYTES POUR L'AMÉLIORATION D'UN BIOCIDE
  申请人：CERADIS BV

  公开号：WO2013133705A1

  公开（公告）日：2013-09-12

  The invention relates to a composition comprising a polyelectrolyte complex of a polyanion and a polycation, and comprising at least one biocide. A preferred composition comprises lignosulfonate and chitosan, preferably in relative a amount of from 1:2 to 60:1 (w/w). The invention further relates to methods for generating a composition according to the invention, and to uses of a mixture according to the invention for protecting an agricultural plant or plant part against a pathogen.