4-dimethylsilanephenol | 31353-78-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-dimethylsilanephenol
• 英文别名: 4-(dimethylsilyl)phenol；p-(Dimethylsilyl)-phenol；p-Dimethylhydrosilylphenol；4-Dimethylsilylphenol
• CAS: 31353-78-3
• 化学式: C₈H₁₂OSi
• 分子量: 152.268
• InChiKey: ZHZKBLNIYNFGKT-UHFFFAOYSA-N

物化性质

• 沸点：
  220.3±23.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.09
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  光气 、 4-dimethylsilanephenol 在 三乙胺 作用下， 生成 Bis-(p-dimethylsilylphenyl)carbonat
  参考文献：
  名称：

  Mironov,V.F. et al., Journal of general chemistry of the USSR, 1973, vol. 43, p. 614 - 617

  摘要：

  DOI：
• 作为产物：
  描述：

  4-dimethylsilylphenoxydimethylsilane 在 sodium methylate 作用下， 以 甲醇 、 乙醚 为溶剂， 生成 4-dimethylsilanephenol 、 苯酚
  参考文献：
  名称：

  Polymerization of arylene bis-silanols

  摘要：

  本发明涉及制备某些高度纯净的芳基双硅醇以及制备五种新的芳基双硅醇的方法，以及使用光气作为聚合促进剂或催化剂聚合这些和其他芳基双硅醇的程序，以获得具有特征结构的高度纯净、高分子量的芳基-硅氧烷聚合物：##STR1## 其中Y是芳基或取代芳基基团；R和R'是相同或不同的烷基、取代烷基或苯基，x范围从约1到3，n范围从约300到1500；所述聚合物的分子量（数均值）为100,000及以上。优选的聚合物是芳基硅氧烷碳酸酯聚合物，当层压到聚碳酸酯板或玻璃上时，在高达400°F的温度下保持其透明度、稳定性和与所述基板的粘附性。这种聚合物对于制备飞机和相关航空航天器的挡风玻璃和舱盖的高温中层材料的配方非常有用。

  公开号：

  US04366323A1

文献信息

• Heme Protein Catalysts for Carbon-Silicon Bond Formation In Vitro and In Vivo
  申请人：California Institute of Technology

  公开号：US20170218346A1

  公开（公告）日：2017-08-03

  The present invention provides compositions and methods for catalyzing the formation of carbon-silicon bonds using heme proteins. In certain aspects, the present invention provides heme proteins, including variants and fragments thereof, that are capable of carrying out in vitro and in vivo carbene insertion reactions for the formation of carbon-silicon bonds. In other aspects, the present invention provides methods for producing an organosilicon product, the method comprising providing a silicon-containing reagent, a carbene precursor, and a heme protein; and combining the components under conditions sufficient to produce an organosilicon product. Host cells expressing the heme proteins are also provided by the present invention.

  本发明提供了利用血红素蛋白催化碳硅键形成的组合物和方法。在某些方面，本发明提供了能够进行体外和体内碳烯插入反应以形成碳硅键的血红素蛋白，包括其变体和片段。在其他方面，本发明提供了生产有机硅产物的方法，该方法包括提供含硅试剂、碳烯前体和血红素蛋白；并在足以产生有机硅产物的条件下将这些组分结合在一起。本发明还提供了表达血红素蛋白的宿主细胞。
• Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
  作者：S. B. Jennifer Kan、Russell D. Lewis、Kai Chen、Frances H. Arnold

  DOI：10.1126/science.aah6219

  日期：2016.11.25

  experiments using cytochrome c from Rhodothermus marinus improved the reaction to be 15 times more efficient than industrial catalysts. Science, this issue p. 1048; see also p. 970 Heme proteins can catalyze the formation of carbon–silicon bonds. Enzymes that catalyze carbon–silicon bond formation are unknown in nature, despite the natural abundance of both elements. Such enzymes would expand the catalytic

  使碳-硅键栩栩如生 含硅的有机化合物对于从聚合物到半导体的许多应用都很重要。然而，用于产生碳-硅键的催化剂通常需要昂贵的痕量金属或寿命有限。借用一些金属酶催化其他稀有卡宾插入反应的能力，Kan 等人。使用血红素蛋白在一系列条件和底物上形成碳-硅键（参见 Klare 和 Oestreich 的观点）。使用来自 Rhodothermus marinus 的细胞色素 c 进行的定向进化实验将反应效率提高了 15 倍于工业催化剂。科学，这个问题 p。1048; 另见第。970 血红素蛋白可以催化碳-硅键的形成。尽管两种元素天然丰富，但催化碳-硅键形成的酶在自然界中是未知的。这些酶将扩展生物学的催化库，使生命系统能够进入以前只对合成化学开放的化学空间。我们发现血红素蛋白在生理条件下通过卡宾插入硅-氢键催化有机硅化合物的形成。该反应在体外和体内进行，以高化学和对映选择性适应广泛的底物。使用定向进化，我们增强了来自
• 실란 화합물의 신규한 합성방법
  申请人：DONGJIN SEMICHEM CO., LTD. 주식회사 동진쎄미켐(119981067679) Corp. No ▼ 120111-0003848BRN ▼137-81-07814

  公开号：KR20150047298A

  公开（公告）日：2015-05-04

  본 발명은 실란 화합물의 신규한 합성방법에 관한 것으로, 더욱 상세하게는 종래의 그리냐드 반응(Grignard reaction) 대신 울만 반응(Ullmann-type reaction)을 이용하여 불순물의 양이 최소화된 실란 화합물을 제조하는 방법, 및 이에 따라 합성된 실란 화합물에 관한 것이다. 본 발명의 실란 화합물 제조방법은 종전의 그리냐드 반응 대신에 울만 반응을 이용함으로써, 불순물의 양을 최소화 할 수 있고, 이로 인해 투습성(WVTR), 경화 후 끈적임 정도(Tacky) 및 시료의 색과 같은 물리적 및 광학적 특성을 극대화 할 수 있으므로, 플렉시블(flexible) OLED소자를 비롯한 광학소자에 유용하게 사용될 수 있다.

  本发明涉及一种新的硅化合物合成方法，更详细地说，涉及一种使用Ullmann型反应而不是传统的格氏试剂反应来制备杂质最少的硅化合物的方法，以及由此合成的硅化合物。本发明的硅化合物制备方法可以通过使用Ullmann型反应而不是传统的格氏试剂反应来最小化杂质的数量，从而最大化物理和光学特性，例如水汽传递率（WVTR），固化后的粘性和样品颜色，因此可以在光学元件中有用，包括柔性OLED器件。
• Synthesis of arylene bis-silanols
  申请人：The United States of America as represented by the Secretary of the Air

  公开号：US04382144A1

  公开（公告）日：1983-05-03

  This invention is directed to the preparation of certain arylene bis-silanols in highly purified form and to the preparation of five new arylene bis-silanols in particular, along with a procedure for polymerizing these and other arylene-type bis-silanols using phosgene as a polymerization promotor or catalyst, to obtain highly purified, high molecular weight arylene-siloxanylene polymers having the characteristic structure: ##STR1## where Y is an arylene or substituted arylene moiety; R and R' are the same or different alkyl group(s), substituted alkyl group(s) or a phenyl group, x ranges from about 1 to 3 and n ranges from about 300 to 1500, said polymers having molecular weights (number average) of 100,000 and higher. Preferred polymers are those arylenesiloxanylenecarbonate polymers which, when laminated to polycarbonate sheets or glass maintain their transparency, stability and adherence to said substrates at temperatures of up to and including 400.degree. F. Such polymers are useful for the formulation of high temperature interlayers for windshields and canopies for aircraft and related aerospace vehicles.

  本发明涉及制备某些高度纯化的芳基双硅醇及特别制备五种新的芳基双硅醇的方法，以及使用光气作为聚合促进剂或催化剂聚合这些和其他芳基双硅醇的方法，以获得具有特征结构的高度纯化、高分子量的芳基-硅氧烷聚合物：##STR1## 其中Y是芳基或取代芳基基团；R和R'是相同或不同的烷基、取代烷基或苯基；x的范围从约1到3，n的范围从约300到1500，所述聚合物的分子量（数均）为100,000及以上。优选的聚合物是那些芳基硅氧烷基碳酸酯聚合物，当与聚碳酸酯板或玻璃层压在一起时，能够在高达400°F的温度下保持其透明度、稳定性和与所述基板的附着性。这种聚合物对于制备飞机和相关航空航天器的挡风玻璃和舱盖的高温中间层具有用处。
• Synthesis of arylene siloxanylene polymers and copolymers
  申请人：The United States of America as represented by the Secretary of the Air

  公开号：US04518759A1

  公开（公告）日：1985-05-21

  This invention is directed to the preparation of certain arylene bis-silanols in highly purified form and to the preparation of five new arylene bis-silanols in particular, along with a procedure for polymerizing these and other arylene-type bis-silanols using phosgene as a polymerization promotor or catalyst, to obtain highly purified, high molecular weight arylenesiloxanylene polymers having the characteristic structure: ##STR1## where Y is an arylene or substituted arylene moiety: R and R' are the same or different alkyl group(s), substituted alkyl group(s) or a phenyl group, X ranges from about 1 to 3 and n ranges from about 300 to 1500, said polymers having molecular weights (number average) of 100,000 and higher. Preferred polymers are those arylenesiloxanylenecarbonate polymers which, when laminated to polycarbonate sheets or glass maintain their transparency, stability and adherence to said substrates at temperatures of up to and including 400.degree. F. Such polymers are useful for the formulation of high temperature interlayers for windshields and canopies for aircraft and related aerospace vehicles.

  本发明涉及制备某些高度纯化的芳基双硅醇以及特别制备五种新的芳基双硅醇的方法，以及使用光气作为聚合促进剂或催化剂聚合这些和其他芳基双硅醇的程序，以获得具有特征结构的高度纯化、高分子量的芳基硅氧烷聚合物：##STR1## 其中Y是芳基或取代芳基基团，R和R'是相同或不同的烷基、取代烷基或苯基，X范围为1至3，n范围为300至1500，所述聚合物的分子量（数均）为100,000及以上。优选的聚合物是那些芳基硅氧烷碳酸酯聚合物，在与聚碳酸酯片或玻璃层压时，能在高达400°F的温度下保持其透明度、稳定性和附着性。这种聚合物对于制备飞机和相关航空航天器的高温中间层很有用。