2-(2-thienyl)-4,5-dimethyl-3,6-dihydro-2H-thiopyran | 117775-54-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: 2-(2-thienyl)-4,5-dimethyl-3,6-dihydro-2H-thiopyran
• 英文别名: 4,5-dimethyl-2-thiophen-2-yl-3,6-dihydro-2H-thiopyran
• CAS: 117775-54-9
• 化学式: C₁₁H₁₄S₂
• 分子量: 210.364
• InChiKey: QQUAHTHZRBKLAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  53.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-噻吩甲醛 、 双(三甲基硫化硅) 生成 2-(2-thienyl)-4,5-dimethyl-3,6-dihydro-2H-thiopyran
  参考文献：
  名称：

  DEGLNNOCENTI, ALESSANDRO;RICCI, ALFREDO;CAPPERUCCI, ANTONELLA;MORDINI, AL+, PHOSPH., SULFUR AND SILICON AND RELAT. ELEM., 58-59,(1991) N-4, C. 117-12+

  摘要：

  DOI：

文献信息

• Silicon-assisted synthesis of thiocarbonyl derivatives and reactivity of dienophilic thioaldehydes
  作者：Antonella Capperucci、Alessandro Degl'Innocenti、Alfredo Ricci、Alessandro Mordini、Gianna Reginato

  DOI：10.1021/jo00026a025

  日期：1991.12

  Treatment of bis(trimethylsilyl) sulfide with CoCl2.6H2O in the presence of aldehydes affords the corresponding thiocarbonyl analogues which can be trapped to avoid polymerization. The sulfurization reaction also takes place in the presence of TfOSiMe3, in which case, besides thioaldehydes, thioketones may be obtained in satisfactory yields. When thioaldehydes are generated with the CoCl2.6H2O method the Diels-Alder reaction with cyclohexadiene occurs with very high selectivity in favor of the endo isomer, whereas when the TfOSiMe3-based method is employed, the stereochemistry of the cycloadduct can be conveniently selected toward endo or exo by varying the molar ratio of the sulfurating agent.
• Cobalt(II) chloride-promoted thionation of carbonyl compounds: a simple access to silyl thio ketones and thio aldehydes
  作者：Alfredo Ricci、Alessandro Degl'Innocenti、Antonella Capperucci、Gianna Reginato

  DOI：10.1021/jo00262a009

  日期：1989.1
• RICCI, A.;DEGL, INNOCENTI A.;CAPPERUCCI, A.;REGINATO, G., J. ORG. CHEM., 54,(1989) N, C. 19-20
  作者：RICCI, A.、DEGL, INNOCENTI A.、CAPPERUCCI, A.、REGINATO, G.

  DOI：——

  日期：——