Dithiobenzoic acid sec-butyl ester | 54255-06-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Dithiobenzoic acid sec-butyl ester
• 英文别名: Butan-2-yl benzenecarbodithioate
• CAS: 54255-06-0
• 化学式: C₁₁H₁₄S₂
• 分子量: 210.364
• InChiKey: UHXCBEFBAVXJAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  57.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PROGRAMMABLE POLYMER DROPLETS AND ASSOCIATED USES
  申请人：ETH Zurich

  公开号：EP4008427A1

  公开（公告）日：2022-06-08

  The present invention pertains to liquid droplets comprising a polymer according to Formula (I) and to their use in an aqueous medium for the controlled uptake of compounds from outside the droplets into the droplets for separation, storage and/or reaction of compounds inside the droplets, as well as associated methods of production of the polymer.

  本发明涉及由符合式（I）的聚合物组成的液滴，及其在水介质中的用途，用于控制液滴外部的化合物吸收到液滴中，以分离、储存和/或反应液滴内部的化合物，以及聚合物的相关生产方法。
• Compositions and methods for inducing immune tolerance
  申请人：The University of Chicago

  公开号：US11253579B2

  公开（公告）日：2022-02-22

  Several embodiments provided in the present disclosure relate to compositions that carry an antigen to which tolerance is desired, the antigen being coupled, bound, or otherwise joined to a targeting moiety, the targeting moiety configured to direct the composition to the liver of a subject. In several embodiments, the antigen in coupled to the targeting moiety by way of a polymeric linker. In several embodiments, the polymeric linker is configured to liberate the antigen in vivo. Methods of using the compositions to reduce and/or prevent unwanted immune responses against an antigen of interest are also provided.

  本公开提供的几个实施方案涉及携带抗原的组合物，抗原与靶向分子偶联、结合或以其他方式连接，靶向分子被配置为将组合物导向受试者的肝脏。在几个实施方案中，抗原通过聚合连接体与靶向分子连接。在几个实施方案中，聚合连接体被配置为在体内释放抗原。此外，还提供了使用组合物减少和/或预防针对相关抗原的不必要免疫反应的方法。
• Block Copolymer Complex Coacervate Core Micelles for Enzymatic Catalysis in Organic Solvent
  申请人：Massachusetts Institute of Technology

  公开号：US20170043197A1

  公开（公告）日：2017-02-16

  Disclosed are complex coacervate core micelles comprising an enzyme capable of hydrolyzing organophosphorus compounds, such as nerve agents, and, for example, their use in remediation or decontamination of stockpiles of chemical weapons.
• COMPOSITIONS AND METHODS FOR INDUCING IMMUNE TOLERANCE
  申请人：The University of Chicago

  公开号：US20220211826A1

  公开（公告）日：2022-07-07

  Several embodiments provided in the present disclosure relate to compositions that carry an antigen to which tolerance is desired, the antigen being coupled, bound, or otherwise joined to a targeting moiety, the targeting moiety configured to direct the composition to the liver of a subject. In several embodiments, the antigen in coupled to the targeting moiety by way of a polymeric linker. In several embodiments, the polymeric linker is configured to liberate the antigen in vivo. Methods of using the compositions to reduce and/or prevent unwanted immune responses against an antigen of interest are also provided.