| 219598-78-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 219598-78-4
• 化学式: C₂₀H₃₁IN₂O₆
• 分子量: 522.38
• InChiKey: QKZDSPCIHKEVBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  29.0
• 可旋转键数：
  13.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  95.12
• 氢给体数：
  2.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  在 PS-SO₃H resin 、 氨 作用下， 生成 N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-4-iodobenzamide
  参考文献：
  名称：

  Pd-Catalyzed synthesis of a tethered soluble polymeric phosphine ligand

  摘要：

  The use of a Pd-catalyzed phosphine-aryl iodide coupling chemistry to prepare soluble polymeric phosphine ligands is described. The lack of sensitivity of the catalyst to the presence of excess phosphine ligand and the fact that the soluble polymeric phosphine ligands are effective ligands for the active catalyst results in a self-replicating ligand synthesis. Ligand or ligand plus catalyst recovery is achieved by solvent precipitation of the polymeric product of this chemistry. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)01976-5
• 作为产物：
  描述：

  3,6,9-三氧杂十一烷-1,11-二胺 生成
  参考文献：
  名称：

  Pd-Catalyzed synthesis of a tethered soluble polymeric phosphine ligand

  摘要：

  The use of a Pd-catalyzed phosphine-aryl iodide coupling chemistry to prepare soluble polymeric phosphine ligands is described. The lack of sensitivity of the catalyst to the presence of excess phosphine ligand and the fact that the soluble polymeric phosphine ligands are effective ligands for the active catalyst results in a self-replicating ligand synthesis. Ligand or ligand plus catalyst recovery is achieved by solvent precipitation of the polymeric product of this chemistry. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)01976-5