N-2,6-bis(2,4,6-trimethylphenyl)phenyl-N-trimethylsilylamino(dichloro)-phosphane | 1071149-52-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-2,6-bis(2,4,6-trimethylphenyl)phenyl-N-trimethylsilylamino(dichloro)-phosphane
• 英文别名: N-trimethylsilyl-N-dichlorophosphanyl-2,6-bis(2,4,6-trimethylphenyl)aniline；TerN(SiMe3)PCl2；N-[2,6-bis(2,4,6-trimethylphenyl)phenyl]-N-(trimethylsilyl)amino-dichlorophosphane；N-dichlorophosphanyl-2,6-bis(2,4,6-trimethylphenyl)-N-trimethylsilylaniline
• CAS: 1071149-52-4
• 化学式: C₂₇H₃₄Cl₂NPSi
• 分子量: 502.539
• InChiKey: FMTCOPVSTVMFQH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.22
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-2,6-bis(2,4,6-trimethylphenyl)phenyl-N-trimethylsilylamino(dichloro)-phosphane 在 gallium(III) trichloride 作用下， 生成 [TerN=P]+[GaCl4]-
  参考文献：
  名称：

  阳离子环状叠氮化磷（III）。

  摘要：

  DOI：

  10.1002/anie.200801674
• 作为产物：
  描述：

  2,6-bis(2,4,6-trimethylphenyl)phenyl-N-trimethylsilylamine 在 正丁基锂 、 三氯化磷 作用下， 以 乙醚 为溶剂， 反应 2.0h， 以45%的产率得到N-2,6-bis(2,4,6-trimethylphenyl)phenyl-N-trimethylsilylamino(dichloro)-phosphane
  参考文献：
  名称：

  Synthesis of 1,3-Dichloro-cyclo-1,3-diphosphadiazanes from Silylated Amino(dichloro)phosphanes

  摘要：

  The synthesis of 1,3-dichloro-cyclo-1,3-diphosphadiazanes [ClP(mu-NR)](2) via elimination of Me3SiCl from silylated amino(dichloro)phosphanes, R-N(SiMe3)PCl2, was studied by different synthetic protocols starting from R-N(H)SiMe3 (R = Si(SiMe3)(3) = Hyp, N(SiMe3)(2), Mes* = 2,4,6-tri-tert-butylphenyl, Ter = 2,4-bis(2,4,6-trimethylphenyl)phenyl, Dipp = 2,6-diisopro-pylphenyl, Dmp = 2,6-dimethylphenyl, Ad = Adamantyl, Trityl = Ph3C, Tos = tosyl = CH3C6H4SO2, n-Oct = n-octyl, and Me3Si).A new synthetic route using trimethylsilyl-substituted amino(dichloro)phosphanes, R-N(SiMe3)PCl2, was developed to form cyclo-diphosph(III)-azanes simply by adding a mixture of RfOH/base (RfOH = hexafluoroisopropanole). By this method electron-rich/-poor aryl-, silyl-, and bissilylamino-substituted cyclo-diphosph(III)-azanes are accessible such as the unprecedented (Me3Si)(2)N-substituted species [ClP(mu-NN(SiMe3)(2))](2) starting from tris(trimethylsilyl)hydrazine and PCl3. Additionally, the difficulties with the preparation of cyclo-diphosphadiazanes depending on the starting materials, solvents, and bases due to the competition of different reaction channels are studied.

  DOI：

  10.1021/ic4017728