N-((4-甲氧基苯基)(对甲苯基)甲基)苯磺酰胺 | 115377-87-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-((4-甲氧基苯基)(对甲苯基)甲基)苯磺酰胺
• 英文名称: N-((4-methoxyphenyl)(p-tolyl)methyl)benzenesulfonamide
• 英文别名: N-[(4-methoxyphenyl)-(4-methylphenyl)methyl]benzenesulfonamide
• CAS: 115377-87-2
• 化学式: C₂₁H₂₁NO₃S
• 分子量: 367.469
• InChiKey: WMROBGDNPKZCCC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  63.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-p-tolyl-[1,3,6,2]dioxazaborocane 、 (E)-N-(4-methoxybenzylidene)benzenesulfonamide 在 bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate 三乙胺 作用下， 以 1,4-二氧六环 为溶剂， 反应 16.0h， 以63%的产率得到N-((4-甲氧基苯基)(对甲苯基)甲基)苯磺酰胺
  参考文献：
  名称：

  Ueda; Saito; Miyaura, Synlett, 2000, # 11, p. 1637 - 1639

  摘要：

  DOI：

文献信息

• The mechanism of hydroxylation of organometallic reagents by 2-sulfonyloxaziridines
  作者：Franklin A. Davis、Jia Wei、Aurelia C. Sheppard、Steven Gubernick

  DOI：10.1016/s0040-4039(00)95605-3

  日期：——

  The hydroxylation of organometallic reagents (RM) by 2-sulfonyloxaziridines 1 is shown to involve a hemiaminal intermediate 2, whose stability is apparently related to the nucleophilicity of the hydroxylated product (ROH).

  已显示2-磺酰基恶唑烷1对有机金属试剂（RM）的羟基化作用涉及半胱氨酸中间体2，该中间体的稳定性显然与羟基化产物（ROH）的亲核性有关。
• Phosphinite- and phosphite-based type I palladacycles as highly active catalysts for addition reactions of arylboronic acids with aldehydes, α,β-unsaturated ketones, α-ketoesters, and aldimines
  作者：Ping He、Yong Lu、Qiao-Sheng Hu

  DOI：10.1016/j.tetlet.2007.05.119

  日期：2007.7

  Phosphinite- and phosphite-based type I palladacycle-catalyzed additions of arylboronic acids with aldehydes, alpha,beta-unsaturated ketones, alpha-ketoesters, and aldimines are described. Our study showed that readily available phosphinite- and phosphite-based type I palladacycles could possess higher catalytic activity than phosphine-based palladacycles and were highly active, practical catalysts. Our study may pave the road for development of optically active phosphinite- and phosphite-based palladacycles for asymmetric catalysis. (C) 2007 Elsevier Ltd. All rights reserved.
• DAVIS, FRANKLIN A.;WEI, JIA;SHEPPARD, AURELIA C.;GUBERNICK, STEVEN, TETRAHEDRON LETT., 28,(1987) N 43, 5115-5118
  作者：DAVIS, FRANKLIN A.、WEI, JIA、SHEPPARD, AURELIA C.、GUBERNICK, STEVEN

  DOI：——

  日期：——