1-tetrahydropyranyloxytetradec-4-yn-7-ol | 183114-32-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1-tetrahydropyranyloxytetradec-4-yn-7-ol
• 英文别名: 1-(oxan-2-yloxy)tetradec-4-yn-7-ol
• CAS: 183114-32-1
• 化学式: C₁₉H₃₄O₃
• 分子量: 310.477
• InChiKey: DXLMRPZZNPMSGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.42
• 重原子数：
  22.0
• 可旋转键数：
  11.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  38.69
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  1-tetrahydropyranyloxytetradec-4-yn-7-ol 在 正丁基锂 、 4-甲基苯磺酸吡啶 作用下， 以 甲醇 为溶剂， 反应 52.5h， 生成 7-Methoxy-tetradec-4-yn-1-ol
  参考文献：
  名称：

  Convenient synthesis of (±)- and (S)-antipode of (4E,7S)-7-methoxytetradec-4-enoic acid, the antimicrobial principle of marine cyanophyte

  摘要：

  The (+/-)- and S-isomers of title compound I were prepared via a short and efficient route. The key features of the synthesis were the use of easily accessible materials, operationally simple reaction protocol and highly enantioselective lipase catalyzed esterification for the generation of the required chiron. Copyright (C) 1996 Published by Elsevier Science Ltd

  DOI：

  10.1016/0957-4166(96)00339-4
• 作为产物：
  描述：

  正辛醛 、 alkaline earth salt of/the/ methylsulfuric acid 在 正丁基锂 、 sodium hydride 、 二甲基亚砜 作用下， 反应 30.75h， 生成 1-tetrahydropyranyloxytetradec-4-yn-7-ol
  参考文献：
  名称：

  Convenient synthesis of (±)- and (S)-antipode of (4E,7S)-7-methoxytetradec-4-enoic acid, the antimicrobial principle of marine cyanophyte

  摘要：

  The (+/-)- and S-isomers of title compound I were prepared via a short and efficient route. The key features of the synthesis were the use of easily accessible materials, operationally simple reaction protocol and highly enantioselective lipase catalyzed esterification for the generation of the required chiron. Copyright (C) 1996 Published by Elsevier Science Ltd

  DOI：

  10.1016/0957-4166(96)00339-4