Benzyl-bis(2-hydroxyethyl)-methylazanium | 148981-13-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl-bis(2-hydroxyethyl)-methylazanium
• CAS: 148981-13-9
• 化学式: C12H20NO2+
• 分子量: 210.29
• InChiKey: TYORFRRVUWSPEW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• FIRE RESISTANT GLAZINGS
  申请人：Varma Karikath Sukumar

  公开号：US20120263903A1

  公开（公告）日：2012-10-18

  An additive for alkali metal silicate solutions, comprising a quaternary ammonium compound having the general formula ( 1 ) R 1 R 2 R 3 R 4 N + OH − , wherein R 1 , R 2 , R 3 and R 4 which may be the same or different represent alkyl groups, hydroxy-substituted alkyl groups, alkaryl groups, hydroxy-substituted alkaryl groups comprising from 1 to 12 carbon atoms, or groups having the general formula —[CH 2 ]n-N + R 5 R 6 R 7 wherein n is an integer having a value of from 1 to 12, the group —[CH 2 ]n may be hydroxy-substituted, and R 5 , R 6 and R 7 which may be the same or different represent alkyl groups, hydroxy-substituted alkyl groups, alkaryl groups or hydroxy-substituted alkaryl groups comprising from 1 to 12 carbon atoms; with the proviso that at least one of the groups R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 represents a hydroxy-substituted alkyl group or a hydroxy-substituted alkaryl group comprising at least 2 carbon atoms wherein the hydroxy substituent is not located on a carbon atom which is bonded to a nitrogen atom.

  一种用于碱金属硅酸盐溶液的添加剂，包括具有一般式（1）R1R2R3R4N+OH−的季铵化合物，其中R1、R2、R3和R4（可以相同也可以不同）代表烷基基团、羟基取代的烷基基团、烷基芳基基团、羟基取代的烷基芳基基团，包括1至12个碳原子，或具有一般式—[CH2]n-N+R5R6R7，其中n为1至12的整数，基—[CH2]n可以是羟基取代的，R5、R6和R7（可以相同也可以不同）代表烷基基团、羟基取代的烷基基团、烷基芳基基团或羟基取代的烷基芳基基团，包括1至12个碳原子；但其中至少一个R1、R2、R3、R4、R5、R6和R7代表至少含有2个碳原子的羟基取代的烷基基团或羟基取代的烷基芳基基团，其中羟基取代物不位于与氮原子键合的碳原子上。
• [EN] USE OF DIETHANOLAMMONIUM DERIVATIVES AS SKIN MOISTURIZER<br/>[FR] UTILISATION DE DÉRIVÉS DE DIÉTHANOLAMMONIUM EN TANT QU'HYDRATANT DE LA PEAU
  申请人：OREAL

  公开号：WO2017029274A1

  公开（公告）日：2017-02-23

  The present invention relates to the cosmetic use as moisturizer for keratin materials, preferably the skin, of one or more diethanolammonium derivatives corresponding to formula (I) below, and also the optical isomers and/or geometrical isomers thereof: (I)

  本发明涉及将一种或多种与下式（I）相对应的二乙醇胺衍生物作为角蛋白材料的化妆品保湿剂，首选是皮肤，以及其光学异构体和/或几何异构体：（I）
• Novel benzothiazepine and bensothiepine compounds
  申请人：Sasahara Takehiko

  公开号：US20070190041A1

  公开（公告）日：2007-08-16

  A pharmaceutical useful as a therapeutic agent and a preventive agent for hyperlipemia, and a pharmaceutical useful as a therapeutic agent and a preventive agent for hepatic disorders associated with cholestasis, particularly, primary biliary cirrhosis and primary sclerosing cholangitis, and a pharmaceutical useful as a therapeutic agent and a preventive agent for obesity, fatty liver and steatohepatitis are provided. A benzothiazepine or benzothiepine compound represented by the following formula (1A) having a thioamide bond and a quaternary ammonium substitutent:

  提供了一种药物，可用作治疗和预防高脂血症的治疗剂和预防剂，以及一种药物，可用作治疗和预防与胆汁淤积有关的肝脏疾病，特别是原发性胆汁性肝硬化和原发性硬化性胆管炎的治疗剂和预防剂，以及一种药物，可用作治疗和预防肥胖症、脂肪肝和脂肪性肝炎的治疗剂和预防剂。化合物的苯并噻吩或苯并噻环代表如下式（1A），具有硫酰胺键和季铵取代基：
• Novel quaternary ammonium compounds
  申请人：Sasahara Takehiko

  公开号：US20070203115A1

  公开（公告）日：2007-08-30

  A method for inhibiting ileal bile acid transporter activity in a subject, comprising administering to said subject an effective amount of a compound represented by formula (1):

  一种抑制回肠胆汁酸转运蛋白活性的方法，包括向该受试者施用一种由式（1）所代表的化合物的有效量：
• Hydrophilic film for ex vivo membrane
  申请人：ETERNAL MATERIALS CO., LTD.

  公开号：US10024847B2

  公开（公告）日：2018-07-17

  The present invention provides a hydrophilic film for an ex vivo membrane, which includes: a substrate; and a hydrophilic coating located on at least one surface of the substrate and formed by a hydrophilic composition, in which the hydrophilic composition includes: (a) a reactive adhesive; (b) a surfactant having reactivity; and (c) optionally a polyol.

  本发明提供了一种用于体外膜的亲水薄膜，其中包括 基底；以及 亲水涂层，位于基底的至少一个表面上，由亲水组合物形成，其中亲水组合物包括 (a) 反应性粘合剂 (b) 具有反应性的表面活性剂；以及 (c) 可选的多元醇。