1-[1-diethylamino-1-phenyl-meth-(E)-ylidene]-3-phenyl-thiourea | 952611-11-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[1-diethylamino-1-phenyl-meth-(E)-ylidene]-3-phenyl-thiourea
• 英文别名: (1E)-1-[diethylamino(phenyl)methylidene]-3-phenylthiourea
• CAS: 952611-11-9
• 化学式: C₁₈H₂₁N₃S
• 分子量: 311.451
• InChiKey: YOBDDWQXJGZQFM-LVZFUZTISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  59.7
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• METHOD FOR CARRYING OUT A MAGNETIC THERAPY OF MALIGNANT NEOPLASMS
  申请人：Obschestvo S Ogranichnnoi Otvetsvennostyu "Perspe

  公开号：EP1897590A1

  公开（公告）日：2008-03-12

  The invention relates to magnetic material physics and to medicine, in particular to magnetotherapy (hyperthermal electromagnetic therapy) of malignant neoplasms. The inventive methods consists in injecting a material particles exhibiting a high-(maximum) magnetocaloric effect into a tumor, wherein said material has a magnetic ordering temperature close (approximately) to a human body temperature and is selected from a group containing precious metals, rare-earth elements (metals) and the alloys or intermetallic compounds thereof. Said method makes it possible to destroy cancer cells without damaging healthy cells and is selected such that it is ecologically pure and non-toxic.

  本发明涉及磁性材料物理学和医学，特别是恶性肿瘤的磁疗法（超高温电磁疗法）。本发明的方法是将具有高（最大）磁热效应的材料颗粒注入肿瘤，其中所述材料的磁有序温度接近（近似）人体温度，并选自包含贵金属、稀土元素（金属）及其合金或金属间化合物的组。所述方法可以在不损害健康细胞的情况下破坏癌细胞，并且是生态纯净无毒的。
• PREPARATION FOR USE IN A METHOD OF MAGNETIC THERAPY OF MALIGNANT NEOPLASMS
  申请人：Tishin, Aleksandr Mettalinovich

  公开号：EP1897590B1

  公开（公告）日：2016-11-09
• THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS
  申请人：Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College

  公开号：EP2007393A2

  公开（公告）日：2008-12-31
• Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers
  申请人：Giordano Anthony

  公开号：US20090306073A1

  公开（公告）日：2009-12-10

  Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of these compounds are also disclosed.
• US8217037B2
  申请人：——

  公开号：US8217037B2

  公开（公告）日：2012-07-10