Piperonyl 7-methyloctanoate | 1000377-95-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: Piperonyl 7-methyloctanoate
• 英文别名: 1,3-Benzodioxol-5-ylmethyl 7-methyloctanoate
• CAS: 1000377-95-6
• 化学式: C₁₇H₂₄O₄
• 分子量: 292.375
• InChiKey: LUCBXMYNOKOPKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  21
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• SUBSTITUTED BENZYL ESTER DERIVATIVE AND USE THEREOF
  申请人：AMINO Yusuke

  公开号：US20090203774A1

  公开（公告）日：2009-08-13

  The present invention relates to a pharmaceutical composition, a food composition or a cosmetic composition, containing one or more kinds of a compound represented by the following formula (I′) wherein R1 is a hydrogen atom, a hydroxyl group, a methoxy group or an ethoxy group, R2 is a hydroxyl group, a methoxy group or an acetoxy group, or R1 and R2 in combination optionally form a methylenedioxy group, R is represented by the following formula wherein Y is an ethylene group or a vinylene group, m and n are each an integer of 0 to 7, which satisfy m+n=2 to 8, and R3 and R4 are each independently a hydrogen atom, a methyl group or an ethyl group, provided that, (1) when R1 is a methoxy group, then R2 is not a hydroxyl group; and (2) when R1 is a hydroxyl group, then R2 is not a hydroxyl group and an acetoxy group. According to the present invention, a stable capsinoid derivative is provided, and a pharmaceutical composition, a food composition, a cosmetic composition and the like containing the derivative as an active ingredient can be provided.

  本发明涉及一种药物组成物、食品组成物或化妆品组成物，含有下式（I'）所表示的一种或多种化合物，其中R1是氢原子、羟基、甲氧基或乙氧基，R2是羟基、甲氧基或乙酰氧基，或者R1和R2在组合时可选地形成一个亚甲二氧基基团，R由下式表示，其中Y是乙烯基或乙烯基，m和n分别是0到7的整数，满足m+n=2到8，R3和R4各自独立地是氢原子、甲基或乙基，前提是：（1）当R1是甲氧基时，则R2不是羟基；（2）当R1是羟基时，则R2不是羟基和乙酰氧基。根据本发明，提供了一种稳定的辣椒素衍生物，并可提供含有该衍生物作为活性成分的药物组成物、食品组成物、化妆品组成物等。
• US7981460B2
  申请人：——

  公开号：US7981460B2

  公开（公告）日：2011-07-19