| 1350888-27-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1350888-27-5
• 化学式: C₂₀H₁₉NO₄
• 分子量: 337.375
• InChiKey: YRUJYSOSXKXPJQ-KRWDZBQOSA-N

反应信息

• 作为反应物：
  描述：

  在 potassium carbonate 、 β-环糊精 作用下， 以 甲醇 、 水 为溶剂， 以99%的产率得到
  参考文献：
  名称：

  Unusual stereo- and chemo-selective photocyclization of chiral α-aminoacid-incorporated 2-acyl benzamides by control of chiral memory

  摘要：

  An unusual decarboxylative photocyclization of 2-acyl benzamides with intramolecular chiral alpha-aminoacids was studied. The reaction exclusively yields bi- and tri-cyclic benzo-oxazepines via distinct chemoselective C-O bond formation. High enantio- and diastereo-selectivities (ee = 87-99% and dr = 85/15-95/5) for the products were achieved. Evidence indicates that the formation of the two chiral carbon centers is controlled by chiral memory. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.11.077