2,5,5-Trimethyl-2-(4-methylphenyl)-1,3-dioxane | 6340-94-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,5,5-Trimethyl-2-(4-methylphenyl)-1,3-dioxane
• CAS: 6340-94-9
• 化学式: C₁₄H₂₀O₂
• 分子量: 220.312
• InChiKey: YPYOQGDGRVXQQA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,2-二甲基-1,3-丙二醇 、 对甲基苯乙酮 在 mesoporous sulfonated silica catalyst 作用下， 反应 0.08h， 以75.1%的产率得到2,5,5-Trimethyl-2-(4-methylphenyl)-1,3-dioxane
  参考文献：
  名称：

  Ketalization of Ketones to 1,3-Dioxolanes and Concurring Self-Aldolization Catalyzed by an Amorphous, Hydrophilic SiO2-SO3H Catalyst under Microwave Irradiation

  摘要：

  The amorphous, mesoporous SiO2-SO3H catalyst with a surface area of 115 m(2) g(-1) and 1.32 mmol H+ per g was very efficient for the protonation of ketones on a 10% (m/m) basis, and the catalyst-bound intermediates can be trapped by polyalcohols to produce ketals in high yields or suffer aldol condensations within minutes under low-power microwave irradiation. The same catalyst can easily reverse the ketalization reaction.

  DOI：

  10.21577/0103-5053.20180039

文献信息

• Ketalization of Ketones to 1,3-Dioxolanes and Concurring Self-Aldolization Catalyzed by an Amorphous, Hydrophilic SiO2-SO3H Catalyst under Microwave Irradiation
  作者：Sandro Barbosa、Myrlene Ottone、Mainara de Almeida、Guilherme Lage、Melina Almeida、David Nelson、Wallans dos Santos、Giuliano Clososki、Norberto Lopes、Stanlei Klein、Lucas Zanatta

  DOI：10.21577/0103-5053.20180039

  日期：——

  The amorphous, mesoporous SiO2-SO3H catalyst with a surface area of 115 m(2) g(-1) and 1.32 mmol H+ per g was very efficient for the protonation of ketones on a 10% (m/m) basis, and the catalyst-bound intermediates can be trapped by polyalcohols to produce ketals in high yields or suffer aldol condensations within minutes under low-power microwave irradiation. The same catalyst can easily reverse the ketalization reaction.