rac-1-(2-tetradecylpalmitoyl)-2-O-hexadecyl-glycero-3-phosphocholine | 111394-18-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: rac-1-(2-tetradecylpalmitoyl)-2-O-hexadecyl-glycero-3-phosphocholine
• 英文别名: 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 7-(hexadecyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-11-tetradecyl-, inner salt, 4-oxide；[2-hexadecoxy-3-(2-tetradecylhexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• CAS: 111394-18-4
• 化学式: C₅₄H₁₁₀NO₇P
• 分子量: 916.444
• InChiKey: VSCPAUFSCQMUTN-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  、 三甲胺 以 乙醇 为溶剂， 生成 rac-1-(2-tetradecylpalmitoyl)-2-O-hexadecyl-glycero-3-phosphocholine
  参考文献：
  名称：

  Generic Phase Behavior of Branched-Chain Phospholipid Monolayers

  摘要：

  Monolayers of chemically modified triple-chain phospholipids have been investigated at the air/water interface using pressure-area isotherms. ne condensed phases of the lipids were characterized by grazing incidence X-ray diffraction (GIXD). Increasing chain length corresponds to a temperature effect, which was quantified for different lipids, depending on the head group structure using isotherm (two-dimensional systems) and DSC (three-dimensional systems) measurements. The combination of structure investigations revealed generic phase diagrams, which describe the phase behavior of multiple-chain lipids in two dimensions. For the 1-acyl-2-O-alkyl phospholipids, the generic phase diagram exhibits only L-2d, LS and LE phases while the exchange of the position of the branched acyl and the non-branched alkyl chains at the glycerol backbone leads to a much richer polymorphism (L-2h, L-2d, Ov, LS, S, tau, LE). Here we present the first experimental evidence of the unusual T phase for multiple-chain lipid monolayers. This phase exhibits an undistorted in-plane lattice despite of tilted chains.

  DOI：

  10.1002/1521-3765(20020715)8:14<3203::aid-chem3203>3.0.co;2-6