钠1,4-二[(2-乙基己基)氧基]-1,4-二氧代-2-丁烷磺酸酯-3,3-二(4-羟基苯基)-2-苯并呋喃-1(3H)-酮(1:1:1) | 89066-78-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 中文名称: 钠1,4-二[(2-乙基己基)氧基]-1,4-二氧代-2-丁烷磺酸酯-3,3-二(4-羟基苯基)-2-苯并呋喃-1(3H)-酮(1:1:1)
• 英文名称: Docusate sodium mixt. with phenolphthalein
• 英文别名: sodium;1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate;3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one
• CAS: 89066-78-4
• 化学式: C40H51NaO11S
• 分子量: 762.9
• InChiKey: KZQUNQQSAWZIRN-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  4.37
• 重原子数：
  53
• 可旋转键数：
  19
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  185
• 氢给体数：
  2
• 氢受体数：
  11

文献信息

• Hydrazone derivatives and uses thereof
  申请人：Bryant W. Robert

  公开号：US20070207093A1

  公开（公告）日：2007-09-06

  The present invention is directed to the use of a compound having the formula wherein R 1 , R 2 , R 3 , R 4 , L 1 , and L 2 are defined herein. The compounds of the present invention are useful as inhibitors of certain taste perceptions and functions. The invention is also directed to compositions comprising a compound according to the above formula.

  本发明涉及使用具有以下式子的化合物，其中R1，R2，R3，R4，L1和L2在此定义。本发明的化合物可用作某些味觉感知和功能的抑制剂。本发明还涉及包含上述式子的化合物的组合物。
• Hydrazone Compounds and Their Use
  申请人：STEIN Philip

  公开号：US20110033393A1

  公开（公告）日：2011-02-10

  The present invention relates to hydrazone compounds of Formula I: and pharmaceutically acceptable salts and stereoisomers thereof, wherein R 1 , R 2 , R 3 , R 4 , L 1 , and L 2 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I as inhibitors of TRPM5 protein.

  本发明涉及式I的腙化合物及其药用可接受的盐和立体异构体，其中R1、R2、R3、R4、L1和L2的定义如规范中所述。本发明还涉及将式I的化合物用作TRPM5蛋白质的抑制剂。
• Rebaudioside C and its stereoisomers as natural product sweetness enhancers
  申请人：International Flavors & Fragrances Inc.

  公开号：EP2880992A2

  公开（公告）日：2015-06-10

  The present invention is directed to the use of rebaudioside C, or a stereoisomer thereof, for enhancing the sweet taste of carbohydrate sweeteners, such as sucrose and fructose. The present invention is also directed to consumables comprising a combination of a carbohydrate sweetener and rebaudioside C, or a stereoisomer thereof.

  本发明是关于使用雷巴第奥甙 C 或其立体异构体来增强蔗糖和果糖等碳水化合物甜味剂的甜味。本发明还涉及由碳水化合物甜味剂和雷巴第奥甙 C 或其立体异构体组合而成的消费品。
• Naringenin and salts thereof for sweetness enhancement
  申请人：INTERNATIONAL FLAVORS & FRAGRANCES INC.

  公开号：EP2923584A1

  公开（公告）日：2015-09-30

  The use of naringenin and a salt thereof to enhance the sweetness of a sweetness modifier and to decrease the amount of a sweetness modifier used in a consumable is provided.

  本发明提供了柚皮苷及其盐的用途，以提高甜味调节剂的甜度并减少甜味调节剂在消费品中的用量。
• TRANSGLUCOSYLATED RUBUS SUAVISSIMUS EXTRACT AND METHODS OF PREPARATION AND USE
  申请人：International Flavors & Fragrances Inc.

  公开号：EP3033949A1

  公开（公告）日：2016-06-22

  Transglucosylated R. suavissimus extract for enhancing the mouthfeel, in particular sugary mouthfeel, of a consumable is provided as is a consumable containing the transglucosylated R. suavissimus extract and further a method of producing the transglucosylated R. suavissimus extract.

  提供了用于增强消费品口感（尤其是含糖口感）的转葡糖基鼠尾草提取物，以及含有转葡糖基鼠尾草提取物的消费品，并进一步提供了生产转葡糖基鼠尾草提取物的方法。