4-(2,2-Dimethylpropyl)pyrrolidin-2-one | 1497268-53-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 4-(2,2-Dimethylpropyl)pyrrolidin-2-one
• CAS: 1497268-53-7
• 化学式: C₉H₁₇NO
• mdl: MFCD21691397
• 分子量: 155.24
• InChiKey: IOAKCJZKHOTURW-UHFFFAOYSA-N

物化性质

• 沸点：
  276.9±9.0 °C(Predicted)
• 密度：
  0.921±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.888
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Compositions and methods for reducing ice crystal formation
  申请人：X-Therma, Inc.

  公开号：US10694739B2

  公开（公告）日：2020-06-30

  The present invention provides peptoid polymers capable of reducing or inhibiting the formation of ice crystals at sub 0° C. temperatures. Also provided are peptoid-peptide hybrids comprising the peptoid polymers provided herein. The peptoid polymers and peptoid-peptide hybrids provided herein are useful for making cryoprotectant solutions. The peptoid polymers, peptoid-peptide hybrids, and cryoprotectant solutions provided herein are useful for making antifreeze solutions, frozen food products, and cosmetic care products. Also provided herein are methods for preserving a tissue, an organ, a cell, or a biological macromolecule using the compositions described herein.

  本发明提供的类肽聚合物能够在 0℃以下的温度下减少或抑制冰晶的形成。本发明还提供了由本发明提供的类肽聚合物组成的类肽-肽混合物。本文提供的蛋白胨聚合物和蛋白胨-肽混合物可用于制造低温保护剂溶液。本文提供的蛋白胨聚合物、蛋白胨-肽混合物和低温保护剂溶液可用于制造防冻溶液、冷冻食品和化妆品护理产品。本文还提供了使用本文所述组合物保存组织、器官、细胞或生物大分子的方法。
• Compositions and Methods for Reducing Ice Crystal Formation
  申请人：X-Therma, Inc.

  公开号：US20170295777A1

  公开（公告）日：2017-10-19

  The present invention provides peptoid polymers capable of reducing or inhibiting the formation of ice crystals at sub 0° C. temperatures. Also provided are peptoid-peptide hybrids comprising the peptoid polymers provided herein. The peptoid polymers and peptoid-peptide hybrids provided herein are useful for making cryoprotectant solutions. The peptoid polymers, peptoid-peptide hybrids, and cryoprotectant solutions provided herein are useful for making antifreeze solutions, frozen food products, and cosmetic care products. Also provided herein are methods for preserving a tissue, an organ, a cell, or a biological macromolecule using the compositions described herein.
• COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION
  申请人：X-THERMA, INC.

  公开号：US20210100238A1

  公开（公告）日：2021-04-08

  The present invention provides peptoid polymers capable of reducing or inhibiting the formation of ice crystals at sub 0° C. temperatures. Also provided are peptoid-peptide hybrids comprising the peptoid polymers provided herein. The peptoid polymers and peptoid-peptide hybrids provided herein are useful for making cryoprotectant solutions. The peptoid polymers, peptoid-peptide hybrids, and cryoprotectant solutions provided herein are useful for making antifreeze solutions, frozen food products, and cosmetic care products. Also provided herein are methods for preserving a tissue, an organ, a cell, or a biological macromolecule using the compositions described herein.
• INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF
  申请人：Annexon, Inc.

  公开号：US20220048930A1

  公开（公告）日：2022-02-17

  Disclosed are compounds of formula I and II and pharmaceutically acceptable salts thereof. Also disclosed are methods of treating a neurodegenerative disorder, an inflammatory disease, an autoimmune disease, an ophthalmic disease or a metabolic disorder using the compounds disclosed herein.
• US9986733B2
  申请人：——

  公开号：US9986733B2

  公开（公告）日：2018-06-05